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TranscriptomicsNext Generation Sequencing Facilitates Quantitative Analysis of miRNAs in hepatic fibrosis and normal tissues.
Aim: Hepatic fibrosis is a major worldwide medical problem and can develop into liver cirrhosis and hepatocellular carcinoma(HCC). Until now, there are no effective drugs for liver ?brosis because the molecular mechanism of progression of liver fibrosis is not fully understood. MicroRNAs (miRNAs) ar...
ORGANISM(S): Rattus norvegicus 
2015-06-04 | E-GEOD-54028 | biostudies-arrayexpress
UnknownC2orf40 inhibits metastasis and regulates chemo-resistance and radio-resistance of nasopharyngeal carcinoma cells by influencing cell cycle and activating the PI3K/AKT/mTOR signaling pathway.
Not available
S-EPMC9175486 | biostudies-literature
TranscriptomicsSpecific sequence determinants of miR-15/107 microRNA gene group targets
Using anti-Argonaute (anti-AGO) antibody co-immunoprecipitation, followed by microarray analyses and downstream bioinformatics, ‘RIP-Chip’ experiments enable direct analyses of miRNA targets. The analyses support four major findings: (i) RIP-Chip studies correlated with total input mRNA profiling pr...
ORGANISM(S): Homo sapiens 
2012-12-11 | E-GEOD-42823 | biostudies-arrayexpress
ProteomicsQuantitative Proteomic Analysis of Aeromonas hydrophila under Potassium Dichromate Stress
This project investigates the proteomic changes in Aeromonas hydrophila under potassium dichromate-induced stress using both data-dependent acquisition (DDA) and data-independent acquisition (DIA) LC-MS/MS strategies. Protein extracts from wild-type and dichromate-treated A. hydrophila cells were en...
ORGANISM(S): Aeromonas Hydrophila Subsp. Hydrophila Atcc 7966 
PXD066345 |
ProteomicsComparative proteomic analysis of two divergent Lingzhi strains
It is reported that heat stress could induce the biosynthesis of ganoderic acids and enhance the production of G. lingzhi polysaccharides. However, heat stress inhibits mycelium growth and reduces hyphal branching, resulting in a significant reduction in mycelial dry weight. Tandem mass tag-based (T...
ORGANISM(S): Ganoderma Lingzhi 
2022-06-15 | PXD034524 |
ProteomicsImproving impact of heparan sulfate on the endothelial glycocalyx abnormalities in atherosclerosis as revealed by glycan-protein interactome
Based on glycan-protein interactome, these data expanded the list of known HSBPs and identified them as key proteins in the development of atherosclerosis.
ORGANISM(S): Homo Sapiens 
PXD042279 |
ProteomicsA BioID-mediated proximity-labeling of human DTX2
To identify human DTX2 proximal proteome, the BioID-DTX2 fusion protein was expressed in DTX2 KO HeLa cells. The biotinylated proteins were pulled down and subjected to mass spectrometry analysis.
ORGANISM(S): Homo Sapiens 
PXD023795 |
ProteomicsDissection of Blood Ecosystem in SARS-CoV-2 Omicron Patients
Here, we systematically profiled clinical phenomes, transcriptomes, proteomes, metabolomes, and immune repertoire of blood cells or plasma in over 1000 specimens from SARS-CoV-2 Omicron patients across multiple disease phases.
ORGANISM(S): Homo Sapiens 
PXD045174 |
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