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Motivation: Monitoring, assessment and prediction of environmental risks that chemicals pose demand rapid and accurate diagnostic assays. A variety of toxicological effects have been associated with explosive compounds TNT and RDX. One important goal of microarray experiments is to discover novel bi...
ORGANISM(S): Eisenia fetida 
Single cells from Ptenpc-/-Smad4pc-/-mTmG+ prostate tumors were isolated into single cells which were FACS-sorted for GFP+ and Tomato+ cells and RNA was purified with TRIzol (Life Technologies). RNA expression profiling was performed using the Mouse Genome 430 2.0 Array (Affymetrix) to generate a P...
ORGANISM(S): Mus musculus 
The earthworm Eisenia fetida is one of the most used species in standardized soil ecotoxicity tests. Endpoints such as survival, growth and reproduction are ecologically relevant but provide little mechanistic insight into the toxicity pathways, especially at the molecular level. To better understan...
ORGANISM(S): Eisenia fetida 
To validate the 244K 60-mer probes using a custom-designed Agilent oligo array and assuming sense orientation of all target sequences. A total of four test arrays were designed assuming both sense and antisense orientations. A sole pooled RNA was used for testing all 4 designs. Two arrays were hybri...
ORGANISM(S): Eisenia fetida 
To validate the 244K 60-mer or 40-mer probes using a custom-designed Agilent oligo array and assuming antisense orientation of all target sequences. A total of four test arrays were designed assuming both sense and antisense orientations. A sole pooled RNA was used for testing all 4 designs. Two arr...
ORGANISM(S): Eisenia fetida 
To validate the 244K 60-mer probes using a custom-designed Agilent oligo array and assuming antisense orientation of all target sequences. A total of four test arrays were designed assuming both sense and antisense orientations. A sole pooled RNA was used for testing all 4 designs. Two arrays were h...
ORGANISM(S): Eisenia fetida 
To validate the 244K 60-mer or 40-mer probes using a custom-designed Agilent oligo array and assuming sense orientation of all target sequences. A total of four test arrays were designed assuming both sense and antisense orientations. A sole pooled RNA was used for testing all 4 designs. Two arrays ...
ORGANISM(S): Eisenia fetida 
Our project focuses on retinoic acid (RA) effect on hepatic lipid homeostasis. Even though RA has more than one receptor including retinoids x receptor (RXR) and retinoic acid receptor (RAR), most probably, RA effect on lipid homeostasis is mediated by RXR and its partners such as PXR, FXR, and PPAR...
ORGANISM(S): Mus musculus 
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