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TranscriptomicsThe epithelial splicing factors ESRP1 and ESRP2 positively and negatively regulate alternative splicing events
Epithelial Splicing Regulatory Proteins 1 and 2 (ESRP1 and ESRP2) are recently discovered epithelial-specific RNA-binding proteins that promote splicing of the epithelial variant of the FGFR2, ENAH, CD44, and CTNND1 transcripts. To catalogue a larger set of splicing events under the regulation of t...
ORGANISM(S): Homo sapiens 
2010-08-18 | E-GEOD-17468 | biostudies-arrayexpress
MetabolomicsMetabolomic Profiling of Mice Serum during Toxoplasmosis Progression Using Liquid Chromatography-Mass Spectrometry
Better understanding of the molecular changes associated with disease is essential for identifying new routes to improved therapeutics and diagnostic tests. The aim of this study was to investigate the dynamic changes in the metabolic profile of mouse sera during T. gondii infection. We carried out ...
2017-01-25 | MTBLS216 | MetaboLights
TranscriptomicsGenome-wide gene expression profiles in lung tissues of pig breeds differing in resistance to porcine reproductive and respiratory syndrome virus
Porcine reproductive and respiratory syndrome caused by porcine reproductive and respiratory syndrome virus (PRRSV) is an infectious disease characterized by severe reproductive deficiency in pregnant sows, respiratory symptoms in piglets, and high mortality. In this study, we employed Affymetrix mi...
ORGANISM(S): Sus scrofa 
2013-07-30 | E-GEOD-49306 | biostudies-arrayexpress
TranscriptomicsTranscription profiling by array of serum microRNAs in rat livers to screen for specific biomarkers to be used in diagnosis of compound- and herb-induced liver injury.
In this study, we employed a strategy to screen miRNA expression profiles in liver tissue by miRCURY LNA(tm) microRNA array analysis followed by TaqMan probe-based quantitative reverse transcription-PCR (qRT-PCR) to validate the miRNA expression profiles in serum and liver of two parallel rat drug-i...
ORGANISM(S): Rattus norvegicus 
2012-09-08 | E-MEXP-3364 | biostudies-arrayexpress
GenomicsIdentification of a novel set of DNA methylation markers in bladder cancer using MBD-methylCap/seq and urine DNA screening in a Chinese population
The aim of the present study was to identify novel DNA methylation markers in bladder cancer (BCa) through genome-wide profiling of bladder cancer cell lines and subsequent MSP screening in urine samples. Experimental Design: MBD methylCap/seq was carried out to screen differentially methylated CpG ...
ORGANISM(S): Homo sapiens 
2012-04-30 | E-GEOD-33839 | biostudies-arrayexpress
UnknownLower serum uric acid and impairment of right cerebral hemisphere structural brain networks are related to depressive symptoms in cerebral small vessel disease: A cross-sectional study.
Not available
S-EPMC10950715 | biostudies-literature
UnknownSuper mitochondria-enriched extracellular vesicles enable enhanced mitochondria transfer.
Not available
S-EPMC12559409 | biostudies-literature
TranscriptomicsDynamics of gene expression changes in epithelial and mesenchymal HMLER cell lines transitioning from suspension 3D culture to adhesion cultures
In order to metastasize, few cells need to detach from the primary tumor, and transition through the circulation to distant sites to establish new solid tumor metastases. The gene expression changes occurring between these transitions are poorly understood, and controversial findings have been repor...
ORGANISM(S): Homo sapiens 
2015-07-10 | E-GEOD-70279 | biostudies-arrayexpress
MetabolomicsSerum Metabolic Profiling of Oocyst-Induced Toxoplasma gondii Acute and Chronic Infections in Mice Using Mass-Spectrometry
Toxoplasma gondii is an obligate intracellular parasite causing severe diseases in immunocompromised individuals and congenitally infected neonates, such as encephalitis and chorioretinitis. This study aimed to determine whether serum metabolic profiling can (i) identify metabolites associated with ...
2018-04-16 | MTBLS418 | MetaboLights
UnknownConstruction of a niche-specific spinal white matter-like tissue to promote directional axon regeneration and myelination for rat spinal cord injury repair.
Not available
S-EPMC8661248 | biostudies-literature
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