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TranscriptomicsTranscription profiling of human MCF-7 cells with inducible LMO4 and DN-Clim expression
The nuclear LIM-only protein LMO4 is upregulated in breast cancer, especially estrogen receptor negative tumors, and its overexpression in mice leads to hyperplasia and tumor formation. Here, we show that deletion of LMO4 in the mammary glands of mice leads to impaired lobuloalveolar development due...
ORGANISM(S): Homo sapiens 
2008-11-07 | E-GEOD-7382 | biostudies-arrayexpress
GenomicsThe glucose-sensing transcription factor MLX promotes myogenesis via myokine signaling
Metabolic stress and changes in nutrient levels modulate many aspects of skeletal muscle function during aging and disease. Growth factors and cytokines secreted by skeletal muscle, known as myokines, are important signaling factors but it is largely unknown whether they modulate muscle growth and d...
ORGANISM(S): Mus musculus 
2015-11-11 | E-GEOD-74678 | biostudies-arrayexpress
UnknownFlexibility between the protease and helicase domains of the dengue virus NS3 protein conferred by the linker region and its functional implications.
Not available
S-EPMC2881804 | biostudies-literature
ProteomicsDesulfovibrio marinus single-subunit oligosaccharyltransferase and its human IgG substrates
Glycoproteomics data about glycan attachment of human IgG catalyzed by a previously uncharacterized single-subunit oligosaccharyltransferase (ssOST) from the bacterium Desulfovibrio marinus, namely DmPglB.
ORGANISM(S): Escherichia Coli (ncbitaxon:562) Homo Sapiens (ncbitaxon:9606) Desulfovibrio Marinus (ncbitaxon:370038) 
2025-05-28 | MSV000098017 | MassIVE
MetabolomicsThe Inhibition of B7H3 by 2-HG Accumulation Is Associated With Downregulation of VEGFA in IDH Mutated Gliomas
B7H3 (also known as CD276) is a co-stimulator checkpoint protein of the cell surface B7 superfamily. Recently, the function beyond immune regulation of B7H3 has been widely studied. However, the expression preference and the regulation mechanism underlying B7H3 in different subtypes of gliomas is ra...
2021-05-26 | MTBLS2692 | MetaboLights
UnknownVisualizing the deep cerebellar nuclei using quantitative susceptibility mapping: An application in healthy controls, Parkinson's disease patients and essential tremor patients.
Not available
S-EPMC9921226 | biostudies-literature
UnknownEffects of Chinese Medicine Tong xinluo on Diabetic Nephropathy via Inhibiting TGF- β 1-Induced Epithelial-to-Mesenchymal Transition.
Not available
S-EPMC4016864 | biostudies-literature
UnknownThe modern spectrum of biopsy-proven renal disease in Chinese diabetic patients-a retrospective descriptive study.
Not available
S-EPMC5877445 | biostudies-literature
TranscriptomicsMLX transcriptional regulation in muscle cells
This study set out to identify MLX transcriptional targets in muscle cells. C2C12 Myoblasts were virally transduced to increase MLX activity, by overexpression of the wild-type protein; and to decrease MLX activity by overexpression of a dominant negative MLX protein and by shRNA induced knockdown o...
ORGANISM(S): Mus musculus 
2016-01-04 | E-GEOD-70028 | biostudies-arrayexpress
UnknownEvaluation of the efficacy of Abelmoschus manihot (L.) on diabetic nephropathy by analyzing biomarkers in the glomeruli and proximal and distal convoluted tubules of the kidneys
Not available
S-EPMC10427220 | biostudies-literature
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