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The objective of the present study was to investigate gene expression profiles of human Cumulus cells isolated from oocytes at metaphase II stage, under controlled ovarian stimulation (COS) cycle and to evaluate the relationship of embryo quality with molecular signatures in Cumulus cells. This stu...
ORGANISM(S): Homo sapiens 
Kai-Xin-San (KXS) is one of the classic famous traditional Chinese medicine prescriptions for amnesia, which has been applied for thousands of years. Modern pharmacological research has found that KXS has significant therapeutic efficacy on nervous system diseases, which is related to its antioxidan...
2023-12-21 | MTBLS8806 | MetaboLights
This experiement aims to know what the differences of protein translation are in the bone marrow derived macro-phages(BMDMs) from WT mice and Elp3 KO mice. We treated the BMDMs with or without IL-4 for 4 hours.
ORGANISM(S): Mus musculus (Mouse) 
2022-09-12 | PXD033962 | Pride
Alternative macrophages are critical in parasites defense, the resolution of inflammation and wound healing. RNA modifications, which are defined as post-transcriptional changes in the chemical composition of RNA molecules, are involved in the immune response.Among tRNA-modifying enzymes which targe...
ORGANISM(S): Mus musculus (Mouse) 
2022-09-12 | PXD023588 | Pride
This dataset corresponds to the proteomic analysis presented in Figure 6A of the manuscript “Obesity-driven microbial GABA depletion promotes metabolic rewiring and colorectal cancer progression.” We performed Drug Affinity Responsive Target Stability (DARTS) and co-immunoprecipitation proteomics us...
ORGANISM(S): Homo sapiens (Human) 
2026-06-21 | PXD069744 | Pride
The aim of the current study is to identify DNA methylation markers associated with rheumatic heart disease with secondary pulmonary arterial hypertension (RHD-PAH). Genome-wide DNA methylation study is performed among 6 RHD-PAH patients and 6 healthy controls using Illumina HumanMethylation 450K ar...
ORGANISM(S): Homo sapiens 
Kidney tissue samples were ground and pulverized in liquid nitrogen and transferred into low protein binding tubes and lysed with 300 µL lysis buffer supplemented with 1 mM PMSF. Then, samples were further lysed with sonication on ice. The parameters were set as 1s/1s intervals, 3 min, and 80 Watts ...
ORGANISM(S): Mus Musculus 
2022-09-19 | PXD036837 |
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