Sort   by:  
 Page size 
ProteomicsPptc7 is an essential phosphatase for promoting mammalian mitochondrial metabolism and biogenesis
Mitochondrial proteins are replete with phosphorylation; however, the origin, abundance, and functional relevance of these modifications are largely unclear. Nonetheless, mitochondria possess multiple resident phosphatases, suggesting that protein dephosphorylation may be broadly important for mitoc...
ORGANISM(S): Mus musculus (Mouse) 
2019-05-29 | PXD012743 | Pride
Mitochondia Pptc7 Phosphoproteome 
MetabolomicsGNPS - Data files for manuscript - Selected ion monitoring for orbitrap-based metabolomics
Please open README-data-for-SIM-paper-20240210.doc for details.
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2024-02-14 | MSV000094084 | GNPS
UnknownRapid generation of drug-resistance alleles at endogenous loci using CRISPR-Cas9 indel mutagenesis.
Not available
S-EPMC5322889 | biostudies-literature
ProteomicsCARM1 substrate identification
The goal of the project was global identification of CARM1 substrates. Arginine methylation landscapes were profiled and compared in wild type and CARM1 knockout cells to determine in vivo substrates of CARM1.
ORGANISM(S): Homo sapiens (Human) 
2017-07-03 | PXD005871 | Pride
Mcf7 Mda-mb-231 Orbitrap fusion lumos Bottom-up Arginine methylation 
TranscriptomicsSimilarity of PDXs between passages and lineages using Affymetrix mRNA expression data
PDX tumors at various passages post first implantation in nude mice PDX tumors were profiled at different passages when they reached ~400mm3
ORGANISM(S): Homo sapiens 
2016-03-02 | E-GEOD-78806 | biostudies-arrayexpress
TranscriptomicsDetecting novel low-abundant transcripts in Drosophila
Increasing evidence suggests that low-abundant transcripts may play fundamental roles in biological processes. In an attempt to estimate the prevalence of low-abundant transcripts in eukaryotic genomes, we performed a transcriptome analysis in Drosophila using the SAGE technique. We collected 244,31...
ORGANISM(S): Drosophila melanogaster 
2005-06-03 | E-GEOD-2347 | biostudies-arrayexpress
ProteomicsProfiling the diversity of agonist-selective effects on the proximal proteome environment of G protein-coupled receptors
G-protein coupled receptors (GPCRs) regulate various aspects of cellular behavior and represent actionable targets for drug discovery. Activation of specific signaling pathways downstream of G-protein coupled receptors (GPCRs) or targeting the receptors at selected cellular locations has the potenti...
ORGANISM(S): Homo Sapiens 
2024-03-31 | PXD031393 | panorama
TranscriptomicsA Chondrogenic Molecule that Repairs Cartilage by Transcriptional Regulation of CBF-beta
Osteoarthritis (OA) is a degenerative joint disease that involves destruction of articular cartilage and eventually leads to disability. Mesenchymal stem cells (MSCs) reside in healthy and diseased cartilage, and through their chondrogenic potential may provide a strategy for cartilage repair. To th...
ORGANISM(S): Homo sapiens 
2012-05-01 | E-GEOD-35546 | biostudies-arrayexpress
ProteomicsIdentification of the target proteins for compound 1
In this project, we used biotin-labeled compound 1 to pull down proteins in U2OS cell lysates with or without the competition of free compound 1, and then to identify the cellular binding of compound 1.
ORGANISM(S): Homo Sapiens 
2022-06-24 | PXD034927 |
ProteomicsHigh-Throughput Single Cell Proteomics Enabled by Multiplex Isobaric Labeling in a Nanodroplet Sample Preparation Platform
Single cell proteomics data from three murine cell lines (Raw, SVEC4-10, C10) and HeLa cell lysate. Samples were digested with trypsin and labeled with TMT 10-Plex on a small scale using nanoPOTS, followed by LC-MS/MS analysis.
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) Mus Musculus (ncbitaxon:10090) 
2019-07-19 | MSV000084110 | MassIVE
Sort   by:  
 Page size