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MetabolomicsCell Membrane Remodeling Mediates Polymyxin B Resistance in Klebsiella pneumoniae: An Integrated Proteomics and Metabolomics Study
Polymyxin B (PB) is introduced into the clinic as the last-line therapy against carbapenem-resistant Klebsiella pneumoniae (CRKP). Unfortunately, increased resistance to PB in Klebsiella pneumoniae (K. pneumoniae) has threatened global health. Resistance of K. pneumoniae ...
2022-03-04 | MTBLS4132 | MetaboLights
ProteomicscircMAN1A2_009-pulled down proteins in HeLa cells
CircRNA pulldown assays were conducted to identify proteins interacting with circMAN1A2_009. In summary, HeLa cell protein extracts were incubated with biotin-labeled circMAN1A2_009 probes obtained from Tsingke Biotechnology, China, at room temperature for 1h. Subsequently, streptavidin magnetic bea...
ORGANISM(S): Homo sapiens (Human) 
2025-05-07 | PXD052372 | Pride
Circman1a2_009 Hela Pull-down assays 
UnknownAlterations in the "Gut-Liver Axis" on Rats with Immunological Hepatic Fibrosis.
Not available
S-EPMC10539088 | biostudies-literature
UnknownWine- and stir-frying processing of Cuscutae Semen enhance its ability to alleviate oxidative stress and apoptosis via the Keap 1-Nrf2/HO-1 and PI3K/AKT pathways in H2O2-challenged KGN human granulosa cell line.
Not available
S-EPMC11094956 | biostudies-literature
MetabolomicsHuman umbilical cord-derived mesenchymal stem cells ameliorate perioperative neurocognitive disorder by inhibiting inflammatory responses and activating BDNF/TrkB/CREB signaling pathway in aged mice

BACKGROUND: Perioperative neurocognitive disorder (PND) is a key complication affecting older individuals after anesthesia and surgery. Failure to translate multiple pharmacological therapies for PND from preclinical studies to clinical settings has necessitated the exploration o...

2023-07-25 | MTBLS7759 | MetaboLights
ProteomicsProteome of follicular Fluid from lean and overweight/obese women with PCOS and that of healthy controls
Polycystic ovary syndrome (PCOS) is typically characterized by oligo or anovulation, hyperandrogenism and polycystic ovarian morphology, affecting 5-20% of women of reproductive age [1]. It has drawn significant attention as a major cause of anovulatory infertility and the syndrome of metabolic, rep...
ORGANISM(S): Homo sapiens (Human) 
2019-10-31 | PXD013937 | Pride
Human Pcos Tmt 
UnknownA Novel Banana Mutant "RF 1" (Musa spp. ABB, Pisang Awak Subgroup) for Improved Agronomic Traits and Enhanced Cold Tolerance and Disease Resistance.
Not available
S-EPMC8496975 | biostudies-literature
UnknownPKMYT1 kinase ameliorates cisplatin sensitivity in osteosarcoma.
Not available
S-EPMC12092789 | biostudies-literature
UnknownSNP-based and haplotype-based genome-wide association on drug dependence in Han Chinese.
Not available
S-EPMC10919046 | biostudies-literature
UnknownLow Innate Immunity and Lagged Adaptive Immune Response in the Re-Tested Viral RNA Positivity of a COVID-19 Patient.
Not available
S-EPMC8295488 | biostudies-literature
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