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UnknownRandomized phase III trial of induction chemotherapy with docetaxel, cisplatin, and fluorouracil followed by surgery versus up-front surgery in locally advanced resectable oral squamous cell carcinoma.
Not available
S-EPMC5569675 | biostudies-literature
ProteomicsApplication of TurboID-mediated proximity labeling and phosphoproteomics for mapping a GSK3 kinase signaling network in Arabidopsis
Transient protein-protein interactions (PPIs), such as those between posttranslational modifying enzymes and their substrates, play key roles in cellular regulation, but are difficult to identify. Here we demonstrate the application of enzyme-catalyzed proximity labeling (PL), using the engineered p...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2023-05-10 | PXD017085 | Pride
Proximity labeling Turboid Mass spectrometry Protein interactome Protein-protein interaction Gsk3 kinase Phosphoproteomics Plant Biotinylation 
GenomicsGenome-Wide Association Studies in Upper Gastrointestinal Cancers (Asian)

This project aims to conduct genome-wide association studies (GWAS) in two anatomically different upper gastrointestinal (UGI) cancer sites in two populations with distinctly different disease rates and genetic profiles. One population has very high rates for both esophageal squamous cel...

phs000361.v1.p1 | EGA
ProteomicsPhotoregulatory Protein Kinases Fine-tune Plant Photomorphogenesis by Directing a Bifunctional Phospho-code on HY5
The core regulatory mechanisms affecting the function of ELONGATED HYPOCOTYL 5 (HY5) during plant photomorphogenesis include dynamics in the transcriptional activity and protein stability of HY5 in response to changes in ambient light; however, little is known about the mediators of these processes....
ORGANISM(S): Arabidopsis Thaliana 
2024-02-07 | PXD049266 |
ProteomicsLarge-scale and high-resolutionmass spectrometry-based proteomics profiling defines molecular subtypes of esophageal cancer for therapeutic targeting
Esophageal cancer (EC) is anaggressive cancer type without clinically relevant molecular subtypes defined, which hinders the development of effective strategies forEC treatment. Here, we reporteda large-scale, high-resolution massspectrometry-based proteomicand phosphoproteomics profiling of EC tumo...
ORGANISM(S): Trichuris Sp. Ex Homo Sapiens Jp-2011 
2021-07-05 | PXD021701 |
ProteomicsThe potential binding proteins of FOXQ1 were detected by mass spectrometry technology, laying the foundation for the subsequent in-depth study of its molecular mechanism
First, Flag-FOXQ1 was overexpressed in HCT-116 cells. Subsequently, the Flag-FOXQ1 complex was enriched via immunoprecipitation (IP) technology. The complex was then washed four times with phosphate-buffered saline (PBS), denatured in loading buffer by boiling, and separated via gel electrophoresis ...
ORGANISM(S): Homo Sapiens 
PXD064807 |
ProteomicsSpatial-region-resolved proteomic map reveals mechanism of COVID-19-associated heart injury
Coronavirus disease 2019 (COVID-19) induces diverse clinical manifestations accompanied by multi-organ dysfunction. Of these, heart complications are the most life threatening. Direct myocardial and vascular injuries due to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) drive systemic ...
ORGANISM(S): Homo Sapiens 
2022-01-26 | PXD031249 |
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