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UnknownLead/Drug Discovery from Natural Resources.
Not available
S-EPMC9736696 | biostudies-literature
UnknownCorrelation analysis between epicardial adipose tissue and acute coronary syndrome.
Not available
S-EPMC11758384 | biostudies-literature
UnknownNOX2-mediated reactive oxygen species are double-edged swords in focal cerebral ischemia in mice.
Not available
S-EPMC9281066 | biostudies-literature
UnknownMELK promotes Endometrial carcinoma progression via activating mTOR signaling pathway.
Not available
S-EPMC7000338 | biostudies-literature
TranscriptomicsGene expression of rat PSCs cultured on plastic, matrigel and collagen
Activated pancreatic stellate cells produce the fibrotic matrix in chronic pancreatitis and pancreatic cancer. In vitro protocols examining PSC biology have usually involved PSCs cultured on plastic, a non-physiological surface. However, PSCs cultured on physiological matrices e.g. MatrigelTM (norma...
ORGANISM(S): Rattus norvegicus 
2013-01-17 | E-GEOD-43496 | biostudies-arrayexpress
ProteomicsIdentification of the Key Protein Associated with Different Hair Types in Sheep and Goat
Animal-derived fiber has the characteristics of being light, soft, strong, elastic and a good thermal insulator and it is widely used in many industries and traditional products, so it plays an important role in the economy of some countries. Variations among phenotypes of wool fibers, among species...
ORGANISM(S): Ovis Aries Capra Hircus 
PXD036685 |
ProteomicsMosaic PKHD1 variants in polycystic kidney caused aberrant protein profiling of mitochondria and lysosomes
Autosomal recessive polycystic kidney disease (ARPKD) is a severe renal cystic disease mainly caused by PKHD1. However, its genetic cause, pathological features, and mechanism remained unsolved. Our findings may provide new insight on the pathophysiology of the polycystic kidney due to PKHD1 deficie...
ORGANISM(S): Homo Sapiens 
PXD028042 |
ProteomicsAberrant NAD+ metabolism underlies Zika virus-induced microcephaly
ZIKV-infection during pregnancy can cause microcephaly in newborns, yet the underlying mechanisms remain largely unexplored. Here, we reveal extensive and large-scale metabolic reprogramming events in ZIKV-infected mouse brains. We perform a multi-omics study comprising transcriptomics, proteomics, ...
ORGANISM(S): Mus Musculus 
PXD026814 |
ProteomicsArtificial intelligence defines protein-based classification of thyroid nodules
We applied PCT-DIA on a total of 1161 nodules from 1133 patients using either tissue cores (1 mm diameter; 0.5–1 mm depth) punched from regions of interest marked on retrospective FFPE tissue blocks or prospective cytology specimens from FNA aspirates. The samples comprise (i) a discovery set of FFP...
ORGANISM(S): Homo Sapiens 
2022-09-07 | PXD036554 |
ProteomicsA Recombinant Vaccine Targeting Receptor-binding Domain of SARS-CoV-2 Spike Protein Induces Protective Immunity in Mice and Non-human Primates
The novel Coronavirus SARS-CoV-2 causes a respiratory illness called COVID-19 leading to a pandemic. An effective preventive vaccine against this virus is urgently needed.
ORGANISM(S): Severe Acute Respiratory Syndrome Coronavirus 2 
PXD020653 |
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