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MetabolomicsBased on the Metabolomic Approach the Energy Metabolism Responses of Oriental River Prawn Macrobrachium nipponense Hepatopancreas to Acute Hypoxia and Reoxygenation
Hypoxia represents a major physiological challenge for prawns and is a problem in aquaculture. Therefore, an understanding of the metabolic response mechanism of economically important prawn species to hypoxia and re-oxygenation is essential. However, little is known about the intrinsic mechanisms b...
2021-05-17 | MTBLS584 | MetaboLights
ProteomicsThe association between baseline serum lipids and renal outcome in microscopic polyangiitis patients
ANCA associated vasculitis(AAV) is a systemic vasculitis of small vessels, characterzied by injury of vascular endothelial cells induced by abnormally activated neutrophils. Microscopic polyangiitis (MPA) is a member of AAV with a high risk of kidney involvement. Blood lipid disorder promotes endoth...
ORGANISM(S): Homo sapiens (Human) 
2025-01-06 | PXD045969 | Pride
Plasma 
ProteomicsGPX4 immunoprecipitation in Huh7 cells
Huh7 cells with expression of Flag-GPX4 were treated with IGF1. An immunoprecipitation assay was performed, and immunoprecipitates were subjected to masspec analysis.
ORGANISM(S): Human 
2023-02-22 | MSV000091343 | MassIVE
TranscriptomicsSmall RNA profile in Moso Bamboo root and leaf
The small RNA libraries from Moso bamboo (Phyllostachy heterocycla) roots and leaves were constructed by using high definition adapters . The small RNA profiles were analyzed. A collection of micro RNAs with similarity to the micro RNA entries in mirbase were discovered. The putative genomic loci o...
ORGANISM(S): Phyllostachys edulis 
2014-08-01 | E-GEOD-55305 | biostudies-arrayexpress
UnknownBinding Selectivity of Inhibitors toward Bromodomains BAZ2A and BAZ2B Uncovered by Multiple Short Molecular Dynamics Simulations and MM-GBSA Calculations.
Not available
S-EPMC8154142 | biostudies-literature
GenomicsHeterochromatin remodeling by CDK12 contributes to learning in Drosophila
We describe the epigenetic profiling of the H3K9me2 and HP1a in Drosophila third instar larvae before and after CDK12 depletion by RNA interference (RNAi). Here we show that CDK12 regulates heterochromatin dynamics in Drosophila chromosomes. Depletion of CDK12 induces the increased HP1a and H3K9me2 ...
ORGANISM(S): Drosophila melanogaster 
2015-11-02 | E-GEOD-63011 | biostudies-arrayexpress
ProteomicsPSAT1 impairs ferroptosis and reduces immunotherapy efficacy via GPX4 hydroxylation
MDA-MB-231 cells with expression of Flag-GPX4 were treated with IFNg. An immunoprecipitation assay was performed, and immunoprecipitates were subjected to masspec analysis.
ORGANISM(S): Homo Sapiens 
2025-03-01 | PXD061373 |
ProteomicsCombine in silico target fishing, Comparative proteomics analysis and in vitro assays to identify antibacterial effects of a TCM (the leaves of Strobilanthes cusia Kuntze) against the Penicillin resistant Streptococcus pneumoniae
The anti-bacterial mechanism of the leaves of Strobilanthes cusia Kuntze against the Penicillin-resistant Streptococcus pneumoniae were analyzed by the comparative proteomics
ORGANISM(S): Streptococcus Pneumoniae 23f 
2022-12-18 | PXD038886 |
ProteomicsLabel-free serum proteome in the rabbit CAS provocation model
A rabbit CAS provocation model was established to screen potential diagnostic biomarkers using quantitative serum proteomics
ORGANISM(S): Oryctolagus Cuniculus 
PXD036383 |
ProteomicsThe analysis of GSDME-NT binding proteins in the presence or absence of methionine
Our study identify that methionine inhibits N-terminus of GSDME (GSDME-NT) -mediated pyroptosis by dampening its endocytotic degradation. Thus，the binding proteins of GSDME-NT are detected in the presence or absence of Methionine for futher exploration。
ORGANISM(S): Homo Sapiens 
2025-01-19 | PXD059954 |
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