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MetabolomicsMulti-omics integration reveals Yu-Xue-Bi tablets attenuate rheumatoid arthritis via metabolic reprogramming-mediated Piezo1 suppression

As a systemic chronic inflammatory disease, Rheumatoid arthritis (RA) is characterized by progressive inflammation, bone and cartilage destruction, leading to significant disability, reduced lifespan, and increased mortality. The clinical use of conventional medications including nonsteroidal ant...

2026-01-24 | MTBLS13760 | MetaboLights
ProteomicsArabidopsis MORC proteins function in the efficient establishment of RNA directed DNA methylation
The Microrchidia (MORC) family of ATPases are required for transposable element (TE) silencing and heterochromatin condensation in plants and animals, and C. elegans MORC-1 has been shown to topologically entrap and condense DNA. In Arabidopsis thaliana, mutation of MORCs has been shown to reactivat...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2021-07-02 | PXD026674 | Pride
Arabidopsis morc7 
UnknownEvaluating Diagnostic and Prognostic Value of Plasma miRNA133a in Acute Chest Pain Patients Undergoing Coronary Angiography.
Not available
S-EPMC4998688 | biostudies-literature
UnknownIdentification of distinct fatigue trajectories in patients with nasopharyngeal carcinoma undergoing radiotherapy: an observational longitudinal study.
Not available
S-EPMC11923017 | biostudies-literature
MetabolomicsThe Relative Content and Distribution of Absorbed Volatile Organic Compounds in Rats Administered Asari Radix et Rhizoma Are Different between Powder- and Decoction-Treated Groups
Asari Radix et Rhizoma (ARR) is an important traditional Chinese medicine. Volatile organic compounds (VOCs) are the main active constituents of ARR. Research on the metabolite profile of VOCs and the difference of absorbed constituents in vivo after an administration of ARR decoction and powder wil...
2021-02-01 | MTBLS2053 | MetaboLights
UnknownAutomatic identification of suspicious bone metastatic lesions in bone scintigraphy using convolutional neural network.
Not available
S-EPMC8417997 | biostudies-literature
UnknownUltrasound assessment of skin thickness and stiffness: the correlation with histology and clinical score in systemic sclerosis.
Not available
S-EPMC7448329 | biostudies-literature
ProteomicsHistone chaperone ASF1 mediates H3.3-H4 deposition in Arabidopsis
Histone chaperones and chromatin remodelers control nucleosome dynamics, essential for transcription, replication, and DNA repair. The histone chaperone Anti-Silencing Factor 1 (ASF1) plays a central role in facilitating CAF-1-mediated replication-dependent H3.1 deposition and HIRA-mediated replicat...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2022-10-31 | PXD035578 | Pride
Arabidopsis Lcms Proteomics 
UnknownDecidual derived exosomal miR-99a-5p targets Ppp2r5a to inhibit trophoblast invasion in response to CeO2NPs exposure.
Not available
S-EPMC10116836 | biostudies-literature
UnknownAssociation of Gastric Antrum Echodensity and Acute Gastrointestinal Injury in Critically Ill Patients.
Not available
S-EPMC8838069 | biostudies-literature
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