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TranscriptomicsEWS/ATF1 activates Fos and induces soft tissue sarcomas from neural crest-derived cells.
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Mus musculus 
2013-04-04 | E-GEOD-41123 | biostudies-arrayexpress
TranscriptomicsReduction of DNA methylation suppresses colon carcinogenesis through induction of tumor cell differentiation
In this study, we analyzed global gene expressions of colon tumors from DNA hypomethylated and the control mice. We found that DNA hypomethylated tumors express significantly higher levels of intestinal differentiation-related genes when compared with the control tumors. These results suggest that D...
ORGANISM(S): Mus musculus 
2015-08-05 | E-GEOD-60620 | biostudies-arrayexpress
GenomicsPremature termination of in vivo reprogramming leads to cancer development through altered epigenetic regulation [RRBS]
We report a reprogrammable mouse system in which reprogramming factor expression in vivo can be controlled temporally by treatment with doxycycline (Dox). Transient expression of reprogramming factors in vivo results in tumor development in various tissues, consisting of undifferentiated dysplastic...
ORGANISM(S): Mus musculus 
2014-02-13 | E-GEOD-52303 | biostudies-arrayexpress
TranscriptomicsPremature termination of in vivo reprogramming leads to cancer development through altered epigenetic regulation [array]
We report a reprogrammable mouse system in which reprogramming factor expression in vivo can be controlled temporally by treatment with doxycycline (Dox). Transient expression of reprogramming factors in vivo results in tumor development in various tissues, consisting of undifferentiated dysplastic...
ORGANISM(S): Mus musculus 
2014-02-13 | E-GEOD-51786 | biostudies-arrayexpress
TranscriptomicsDifferent levels of canonical Wnt signaling exert distinct roles in the colonic epithelium
There is a gradient of M-NM-2-catenin expression along the colonic crypt axis with the highest levels at the crypt bottom. However, it remains unclear whether different levels of canonical Wnt signaling exert distinct roles in the colonic epithelium. In the present study, we first showed that the ca...
ORGANISM(S): Mus musculus 
2013-01-22 | E-GEOD-41688 | biostudies-arrayexpress
TranscriptomicsPRDM14 Ensures a Naïve Pluripotency by a Dual Mechanism Involving Signaling and Epigenetic Pathways in Mouse Embryonic Stem Cells
Mouse embryonic stem cells (mESCs) fluctuate between a naïve inner cell mass (ICM)-like state and a primed epiblast-like state of pluripotency in serum, but are harnessed exclusively in a distinctive, apparently more naïve state of pluripotency (the ground state) with inhibitors for mitogen-activate...
ORGANISM(S): Mus musculus 
2013-01-18 | E-GEOD-42580 | biostudies-arrayexpress
GenomicsPRDM14 Ensures Naïve Pluripotency through Dual Regulation of Signaling and Epigenetic Pathways in Mouse Embryonic Stem Cells
Mouse embryonic stem cells (mESCs) fluctuate between a naïve inner cell mass (ICM)-like state and a primed epiblast-like state of pluripotency in serum, but are harnessed exclusively in a distinctive, naïve state of pluripotency that more faithfully captures the ICM state (the ground state) with i...
ORGANISM(S): Mus musculus 
2013-01-18 | E-GEOD-42616 | biostudies-arrayexpress
UnknownRole of Scl39a13/ZIP13 in cardiovascular homeostasis.
Not available
S-EPMC9586387 | biostudies-literature
UnknownRivaroxaban or aspirin for patent foramen ovale and embolic stroke of undetermined source: a prespecified subgroup analysis from the NAVIGATE ESUS trial.
Not available
S-EPMC6662613 | biostudies-literature
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