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TranscriptomicsDevelopment of gene expression signatures for miR-340 overexpressing human glioma-initiating cells (GICs)
To identify functional targets of miR-340, we compared the gene expression profiles of miR-340 overexpressing human GICs with the profiles of their parental cells. The precursor form of miR-340 or control miRNA was overexpressed in glioma cells using miRNA lentiviral particles. The cells were incuba...
ORGANISM(S): Homo sapiens 
2015-04-07 | E-GEOD-61078 | biostudies-arrayexpress
TranscriptomicsDevelopment of microRNA (miRNA) expression signatures for human glioma-initiating cells (GICs)
To identify a novel miRNA that is aberrantly expressed in GICs, we analyzed differences in miRNA expression between the human GICs and glioma cell lines and neural stem cells by miRNA microarrays. We examined the miRNA expression profiles of five human GICs that were obtained from human glioma sampl...
ORGANISM(S): Homo sapiens 
2015-04-07 | E-GEOD-61079 | biostudies-arrayexpress
TranscriptomicsDevelopment of microRNA (miRNA) expression signatures for mouse glioma-initiating cells (GICs)
To identify a novel miRNA that is aberrantly expressed in GICs, we analyzed differences in miRNA expression between the mouse GICs, NSCL61 and OPCL61, showing characteristic features of cancer stem cell, and their parental cells by miRNA microarrays. neural stem cells, glioma-initiating cells (GICs)...
ORGANISM(S): Mus musculus 
2015-04-07 | E-GEOD-61080 | biostudies-arrayexpress
TranscriptomicsEffect of progerin on p53-deficient vascular smooth muscle cells
Analysis of p53-deficient (E6-expressing) human vascular smooth muscle cells (VSMCs) that express progerin, a mutated form of lamin A resposible for Hutchinson- Gilford progeria syndrome (HGPS). p53 pathway is associated with HGPS. Results provide insight into molecular mechanisms underlying vascula...
ORGANISM(S): Homo sapiens 
2013-09-22 | E-GEOD-47553 | biostudies-arrayexpress
TranscriptomicsMepenzolate bromide displays beneficial effects in a mouse model of chronic obstructive pulmonary disease
For the clinical treatment of chronic obstructive pulmonary disease (COPD), it is important not only to improve the airflow limitation by bronchodilation but also to suppress emphysema by controlling inflammation. In this study, we have screened for compounds that prevent elastase-induced airspace ...
ORGANISM(S): Mus musculus 
2013-11-13 | E-GEOD-50836 | biostudies-arrayexpress
TranscriptomicsGene expression in the whole brains of two spontaneously hypertensive rat strains at 3 and 6 weeks of age
We examined gene expression profiles in the rat whole brains using genome-wide microarray technology, and determined gene expression profiles in 3 rat strains: normotensive WKY, spontaneously hypertensive rats (SHR), and stroke-prone SHR (SHRSP). To identify candidate genes involved in the genesis o...
ORGANISM(S): Rattus norvegicus 
2014-01-24 | E-GEOD-41452 | biostudies-arrayexpress
ProteomicsPEPPI-MS- and GELFrEE-fractionated E. coli MG1655 whole cell lysate
Supplemental Files accompanying manuscript “PEPPI-MS: polyacrylamide gel-based prefractionation for analysis of intact proteoforms and protein complexes by mass spectrometry”.
ORGANISM(S): Escherichia Coli Str. K-12 Substr. Mg1655 (ncbitaxon:511145) 
2020-04-08 | MSV000085258 | MassIVE
TranscriptomicsGene expression in the adrenal glands of two spontaneously hypertensive rat strains at 3 and 6 weeks of age
We examined gene expression profiles in the rat adrenal glands using genome-wide microarray technology, and determined gene expression profiles in 3 rat strains: normotensive WKY, spontaneously hypertensive rats (SHR), and stroke-prone SHR (SHRSP). To identify candidate genes involved in the genesis...
ORGANISM(S): Rattus norvegicus 
2013-04-16 | E-GEOD-31457 | biostudies-arrayexpress
ProteomicsGene expression profile of epithelial cells from five regions of human intestinal.
Data independent analysis of proteome of patient derived epithelial cell from five regions, duodenum, jejunum, ileum, colon and rectum.
ORGANISM(S): Homo Sapiens (human) 
2023-05-08 | PXD037197 | JPOST Repository
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