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Genome-wide methylation analysis was performed by methylated DNA immunoprecipitation-CGI microarray analysis. A pool of four cancer samples without lymph node metastasis, two pools of four cancer samples with lymph node metastasis, and three metastatic lymph nodes were prepared from the patients, an...
ORGANISM(S): Homo sapiens 
To evaluate involvement of miR-221 and miR-222 in lung cancer, we investigated the effects of miR-221 and miR-222 overexpression on six lung cancer cell lines as well as one immortalized normal human bronchial epithelial cell line. Two cell lines, H3255 and H1299 with no replicates were studied. Ce...
ORGANISM(S): Homo sapiens 
There is a gradient of M-NM-2-catenin expression along the colonic crypt axis with the highest levels at the crypt bottom. However, it remains unclear whether different levels of canonical Wnt signaling exert distinct roles in the colonic epithelium. In the present study, we first showed that the ca...
ORGANISM(S): Mus musculus 
To predict RP58-regulated genes involved in skeletal myogenesis, RNA profiling experiments were performed, comparing RNA derived from skeletal muscle tissue of a RP58+/+ mouse to that from a RP58 knockout (KO) mouse at E18.5. Importantly, well-known dominant-negative inhibitors of muscle differentia...
ORGANISM(S): Mus musculus 
Several human cancers contain a small subpopulation of cells called cancer stem-like cells (CSCs)/cancer initiating cells (CICs), which are defined by the ability of self- renewal, multi-differentiation potential, and tumorigenesis. In current study, we focused on epithelioid sarcoma, which is very ...
ORGANISM(S): Homo sapiens 
Shotgun mass spectrometric analysis of WT and TOPORS KO MDS-L cells
ORGANISM(S): Homo Sapiens (human) 
Mass spectrometric analysis of ubiquitinated proteins in MDS-L cells
ORGANISM(S): Homo Sapiens (human) 
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