Background: Hypertension remains a significant global health challenge, with limited treatment efficacy in many patients. Emerging evidence suggests that gut microbiota plays a crucial role in blood pressure regulation. This study investigates the anti-hypertensive effects of Achyranthes bidentat...
We identify a novel microbiota-driven anti-hypertensive mechanism mediated by Achyranthes bidentata (Ab) extract and gut microbe Dubosiella sp.. Using a hypertensive mouse model induced by L-NAME and a high-salt diet, we show that Ab extract significantly ameliorates hypertension and renal damage...