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TranscriptomicsTranscription profiling and QTL mapping of 60 mice from an F2 sample segregating for diabetes to generate expression trait correlations and expression quantitative trait locus mapping.
Coordinated regulation of gene expression levels across a series of experimental conditions provides valuable information about the functions of correlated transcripts. To map gene regulatory pathways, we used microarray-derived gene expression measurements in 60 individuals of an F2 sample segregat...
ORGANISM(S): Mus musculus 
2008-06-12 | E-GEOD-3330 | biostudies-arrayexpress
TranscriptomicsPotato autopolyploidy
A synthetic autopolyploidy plant series O37 was developed from chromosome doublings of a monoploid (12 chromosome) plant derived from a Solanum phureja background. Monoploid (1x), diploid (2xR3 and 2xR5) and tetraploid (4x) plants were used for gene expression profiling. Total RNA was isolated from ...
ORGANISM(S): Solanum phureja 
2010-07-01 | E-GEOD-5428 | biostudies-arrayexpress
UnknownPositional cloning of a type 2 diabetes quantitative trait locus; tomosyn-2, a negative regulator of insulin secretion.
Not available
S-EPMC3188574 | biostudies-literature
UnknownThe Utah NeoSeq Project: a collaborative multidisciplinary program to facilitate genomic diagnostics in the neonatal intensive care unit.
Not available
S-EPMC11929918 | biostudies-literature
TranscriptomicsA Gene Expression Network Model of Type 2 Diabetes Links Cell Cycle
Insulin resistance is necessary but not sufficient for the development of type 2 diabetes. Diabetes results when pancreatic beta-cells fail to compensate for insulin resistance by increasing insulin production through an expansion of beta-cell mass or increased insulin secretion. Communication betwe...
ORGANISM(S): Mus musculus 
2008-03-14 | E-GEOD-10785 | biostudies-arrayexpress
UnknownLiver and adipose expression associated SNPs are enriched for association to type 2 diabetes.
Not available
S-EPMC2865508 | biostudies-literature
UnknownArtificial intelligence enables comprehensive genome interpretation and nomination of candidate diagnoses for rare genetic diseases.
Not available
S-EPMC8515723 | biostudies-literature
UnknownInterventions to Disrupt Coronavirus Disease Transmission at a University, Wisconsin, USA, August-October 2020.
Not available
S-EPMC8544969 | biostudies-literature
GenomicsA molecular shift in limb identity underlies the convergent evolution and development of feathered feet
The genetic and developmental mechanisms that control the decision between scale and feather growth – two profoundly different epidermal appendages, and an important developmental shift in the evolution of birds from their dinosaurian ancestors – remain poorly understood. Domestic pigeons displa...
ORGANISM(S): Columba livia 
2016-04-03 | E-GEOD-67875 | biostudies-arrayexpress
TranscriptomicsTranscriptome sequencing of the rock pigeon, Columba livia
Deep sequencing of mRNA from the rock pigeon Analysis of ploy(A)+ RNA of different specimens: heart and liver from the rock pigeon (Danish Tumbler, Oriental Frill and Racing)
ORGANISM(S): Columba livia 
2013-02-03 | E-GEOD-39333 | biostudies-arrayexpress
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