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ProteomicsMajor toxin composition of particulate matter from a coal-fired power plant and its proteomics-associated toxicological profiles in the lungs of balb/c mice
Coal-fired power plant is a major method of electricity generation worldwide with serious concerns relating to air pollution. In recent years, fly ash from coal-fired power plants has become a major target of pollution control by worldwide regulatory agencies. In this present study, fly ash particu...
ORGANISM(S): Mus musculus (Mouse) 
2025-08-21 | PXD058082 | Pride
Particulate matter Polyaromatic hydrocarbons Proteomics Coal-fired power plant Heavy metals Pulmonary inflammation 
ProteomicsA general multipronged activation approach for natural product discovery in Actinomycetes 54 actinobacterial strains with genetic and cultivation based activation
LC-MS/MS fermentation extract collection of 54 diverse and non-domesticated actinobacterial strains interrogated with a one-step integrase-mediated genetic- and cultivation-based approach to perturb and activate metabolite production in actinobacteria that has significantly increased accessible meta...
ORGANISM(S): Streptomyces Viridochromogenes (ncbitaxon:1938) Streptomyces Abikoensis (ncbitaxon:97398) Thermoactinomyces Vulgaris (ncbitaxon:2026) Streptomyces Albogriseolus (ncbitaxon:1887) Streptomyces Sampsonii (ncbitaxon:42239) Streptomyces Ardesiacus Streptomyces Fradiae (ncbitaxon:1906) Streptomyces Filipinensis (ncbitaxon:66887) Streptomyces Niveiscabiei (ncbitaxon:164115) Streptomyces Odonnellii (ncbitaxon:1417980) Streptomyces Anandii (ncbitaxon:285454) Streptomyces Thermocarboxydus (ncbitaxon:59299) Streptomyces Flaveolus (ncbitaxon:67297) Streptomyces Albofaciens (ncbitaxon:66866) Micromonospora Maris Streptomyces Luridiscabiei (ncbitaxon:164114) Streptomyces Lavendulae (ncbitaxon:1914) Streptomyces (ncbitaxon:1883) Spirillospora Tritici Streptomyces Kronopolitis (ncbitaxon:1612435) Streptomyces Niveoruber (ncbitaxon:68243) Streptomyces Cyaneochromogenes Streptomyces Lunaelactis (ncbitaxon:1535768) Streptomyces Hirsutus (ncbitaxon:35620) Streptomyces Jeddahensis (ncbitaxon:1716141) Streptomyces Tendae Strain Atcc 19812 Micromonospora Oryzae (ncbitaxon:1530046) Streptomyces Nigrescens (ncbitaxon:1920) Streptomyces Durhamensis (ncbitaxon:68194) Streptomyces Variabilis (ncbitaxon:67372) Micromonospora Aurantiaca (ncbitaxon:47850) Streptomyces Tendae (ncbitaxon:1932) Micromonospora Maritima (ncbitaxon:986711) Streptomyces Globisporus (ncbitaxon:1908) Dactylosporangium Solaniradicis (ncbitaxon:1758122) 
2023-06-22 | MSV000092237 | MassIVE
TranscriptomicsTCF12 Expression Profiles in HNSCC
To investigate the regulation of TCF12 on downstream genes in OSCC, we performed GeneChip analysis using OECM1 expression cell subclones and HSC3 knockdown cell subclones. 4 samples
ORGANISM(S): Homo sapiens 
2015-06-24 | E-GEOD-70186 | biostudies-arrayexpress
TranscriptomicsA long noncoding RNA protects the heart from pathological hypertrophy
The role of long noncoding RNA (lncRNA) in adult hearts is unknown; also unclear is how lncRNA modulates nucleosome remodelling. An estimated 70% of mouse genes undergo antisense transcription1, including myosin heavy chain 7 (Myh7), which encodes molecular motor proteins for heart contraction2. Her...
ORGANISM(S): Homo sapiens 
2014-08-05 | E-GEOD-49716 | biostudies-arrayexpress
ProteomicsComparative effects of standardized Centella asiatica extract (ECa 233) and its active compound mixture on proteomics and mitochondrial function
A standardized extract of Centella asiatica (ECa 233) strengthened the hippocampal synapses, resulting in the memory-enhancing effect. The ratio of the major active compounds in the extract – madecassoside [MDS] and asiaticoside [ASS] – is at 1.5 ± 0.5:1. However, the interactions between MDS and AS...
ORGANISM(S): Homo sapiens (Human) 
2025-08-13 | PXD057572 | Pride
Triterpenoid glycosides Proteomic Mitochondria Centella asiatica extract (eca 233) Sh-sy5y 
TranscriptomicsMetabolic and gene expression changes induced by the naturally occurring deltaNp53 isoform link mTOR pathway and mitochondrial alterations to the progeroid phenotype.
This study is to find the cellular and molecular mechanisms by which a naturally-occurring deltaNp53 isoform causes accelerated aging in humans. The biological function of deltaNp53, which lacks only 40 N-terminal amino acids, represents an example of p53 as a regulator of mammalian aging. When expr...
ORGANISM(S): Homo sapiens 
2014-05-08 | E-GEOD-37271 | biostudies-arrayexpress
GenomicsAn Rtf2 domain-containing protein influences pre-mRNA splicing and is essential for embryonic development in Arabidopsis thaliana
Alternative splicing is prevalent in plants, but little is known about its regulation in the context of developmental and signaling pathways. We describe here a new factor that influences pre-mRNA splicing and is essential for embryonic development in Arabidopsis thaliana. This factor was retrieved ...
ORGANISM(S): Arabidopsis thaliana 
2014-11-14 | E-GEOD-63238 | biostudies-arrayexpress
TranscriptomicsTranscriptome analysis of HepG2 cell with QD655 and QD705 treatments
Discovery time-course genome-wide expression profiles in HepG2 cell with QD655 and QD705 treatments to reveal genotoxicity and chronological regulatory pathway Time-course gene expression profiles of HepG2 cell cline with QD655 and QD705 treatments were analyzed. Total RNA were harvested from 4, 8, ...
ORGANISM(S): Homo sapiens 
2010-09-01 | E-GEOD-21904 | biostudies-arrayexpress
MetabolomicsA longitudinal ¹H NMR-based urinary metabolomics dataset in a birth cohort for childhood atopic diseases

This dataset presents longitudinal urinary metabolomic profiles from 198 children at 1 month, 6 months, 1 year, 3 years and 5 years. It includes demographic data, feeding practices, parental atopy, household income and atopic disease status over time. Total and allergen-specific IgE (mite, egg, c...

2025-07-28 | MTBLS12785 | MetaboLights
UnknownGlobal Impact of the COVID-19 Pandemic on Cerebral Venous Thrombosis and Mortality.
Not available
S-EPMC9194544 | biostudies-literature
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