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Deep-sea hydrothermal vents emit intense infrared (IR) radiation that profoundly shapes microbial ecology and promotes bacterial growth. To investigate the mechanisms underlying IR responsiveness, we isolated Rhodotorula mucilaginosa strain F-J1, a deep-sea yeast. We found that both elevated tempera...
ORGANISM(S): Rhodotorula mucilaginosa 
2026-09-07 | PXD069040 | Pride
We report that a DNA minor groove binding hairpin pyrrole-imidazole (Py-Im) polyamide interferes with RNA polymerase II (RNAP2) activity in cell culture. Genome-wide mapping of RNAP2 binding shows reduction of occupancy preferentially at transcription start sites (TSS), while occupancy at enhancer ...
ORGANISM(S): Homo sapiens 
According to different feeding and treatment conditions, 36 C57BL/6JC rats were randomly divided into normal diet group (WC group), high fat diet group (WF group) and high fat diet + silibinin group (WS group). TMT combined with LC-MS/MS were used to study the expression of WAT in epididymis of HFD-...
ORGANISM(S): Mus musculus (Mouse) 
2020-01-13 | PXD016635 | Pride
Background Extracellular vesicles (EVs) secreted by mesenchymal stromal cells (MSCs) provide significant protection against renal ischemia-reperfusion injury (IRI). Hypoxia is considered an important method for enhancing the tissue repair capabilities of MSCs. However, the specific effects of hypoxi...
ORGANISM(S): Homo sapiens (Human) 
2025-05-07 | PXD057088 | Pride
Toad venom is a traditional Chinese medicine with high medicinal value. The existing quality evaluation standards of it has obvious limitation for lack of protein study. Thus, it’s necessary to screen suitable biomarkers and establish appropriate quality evaluation method for the characteristics of ...
ORGANISM(S): Bufo Gargarizans 
2023-02-27 | PXD040406 |
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