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The cold stress is considered the bottleneck problem limiting the development of red tilapia industry. Fish (initial weight: 72.71±1.32 g) was divided into the cold stressed group (C) and the control normal water temperature group (N). The water temperature was reduced by 2℃ per day from 20℃ to 8℃ i...
ORGANISM(S): Oreochromis sp. 'red tilapia' 
2024-08-15 | PXD052625 | Pride
We isolated mitochondria from fructose-incubated podocytes and performed data-independent acquisition (DIA)-based quantitative proteomics to analyze the global expression level of mitochondrial proteins.
ORGANISM(S): Homo sapiens (Human) 
2026-06-05 | PXD047317 | Pride
We found that adult zebrafish bearing a homozygous hypomorphic mutation in the sec31a gene (sec31anju221) exhibited overt glycogenic hepatopathy. As an efforts to investigate how hepatic metabolic maladaptation happened in sec31anju221 fish, livers were dissected from the adult zebrafish and DIA-MS ...
ORGANISM(S): Danio rerio (Zebrafish) (Brachydanio rerio) 
2024-08-28 | PXD048925 | Pride
Background:Episodic memory loss is a prominent clinical manifestation of Alzheimer's disease(AD), which is closely related to tau pathology and hippocampal impairment. Given the heterogeneity of brain neurons, the precise role of different brain neurons in terms of their sensitivity to tau accumulat...
ORGANISM(S): Mus Musculus 
2023-07-19 | PXD043883 |
Biomolecular condensates are cellular compartments without enveloping membranes, enabling them to dynamically adjust their composition in response to environmental changes through post-translational modifications. A recent study has revealed that interferon-induced ADP-ribosylation (ADPr), which can...
ORGANISM(S): Homo sapiens (Human) 
2025-05-26 | PXD057944 | Pride
The PAF complex (Paf1C) has been shown to regulate chromatin modifications, gene transcription, and PolII elongation. Here, we provide the first genome-wide analysis of chromatin occupancy by the entire PAF complex in mammalian cells. We show that Paf1C is recruited not only to promoters and gene bo...
ORGANISM(S): Mus musculus 
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