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Little is known about the global transcriptional program underlying megakaryocytic (Mk) differentiation, maturation, and apoptosis. Using DNA microarrays and Q-RT-PCR, we examined the transcriptional profile of Mk differentiation human CD34-positive hematopoietic stem and progenitor cells cultured ...
ORGANISM(S): Homo sapiens 
Visceral fat (VF) and subcutaneous fat (SF) are developmentally different tissues with different gene expression. Islet-1 (ISL1), a LIM-homeobox transcription factor with important developmental and regulatory function in islet, neural, and cardiac tissue, is virtually absent in SF but substantially...
ORGANISM(S): Mus musculus 
Animal germline development and fertility relies on paralogs of general transcription factors that recruit RNA polymerase II to ensure cell type-specific gene expression. It remains unclear whether gene expression processes downstream of such paralog-based transcription is distinct from that of can...
ORGANISM(S): Drosophila melanogaster (Fruit fly) 
2024-04-13 | PXD049360 | Pride
Animal germline development and fertility relies on paralogs of general transcription factors that recruit RNA polymerase II to ensure cell type-specific gene expression. It remains unclear whether gene expression processes downstream of such paralog-based transcription is distinct from that of can...
ORGANISM(S): Drosophila melanogaster (Fruit fly) 
2024-04-13 | PXD049375 | Pride
primary mammary cells of the tammar were cultured with 5ug/mL E. coli derived lipoteichoic acid or lipopolysaccharide for four hours. Two control groups where tammar primary mammary cells were cultured for zero and four hours without this stimulant were also used.
ORGANISM(S): Macropus eugenii 
Experiment description 1. Experimental design 1) Authors, laboratory, and contact: Xue-Lin Cui1, Patricia Soteropoulos2, Peter Tolias2, Ronaldo P. Ferraris1: 1Dept. of Pharmacology and Physiology, UMDNJ-New Jersey Medical School, Newark, NJ 07103-2714, 2Center for Applied Genomics, PHRI, 225 Warre...
ORGANISM(S): Rattus norvegicus 
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