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ProteomicsMass Spectrum-based Identification of direct-binding proteins of TAIII-probe
This experiment utilizes a technology platform based on the Ultimate 3000 nano ultra-high-performance liquid chromatography coupled with the Q Exactive Plus high-resolution mass spectrometer, combined with database search software, to perform qualitative (or relative quantitative) analysis of protei...
ORGANISM(S): Homo sapiens (Human) 
2026-02-20 | PXD060766 | Pride
ProteomicsA Quantitative Chemical Proteomics Approach to Profile the Specific Cellular Targets of Andrographolide, a Promising Anticancer Agent that Suppresses Tumor Metastasis
Drug target identification is a critical step towards the understanding of the mechanism of action of a drug, which will help to improve the current therapeutic regime and to expand the drug’s therapeutic potential. However, current in vitro affinity chromatography-based and in vivo activity- based ...
ORGANISM(S): Homo sapiens (Human) 
2019-11-28 | PXD000588 | Pride
Chemical biology  drug targets*  itraq  mass spectrometry Molecular probes*   antitumor agents  metastasis 
UnknownNeoadjuvant Chemoradiotherapy Followed by Surgery Versus Surgery Alone for Locally Advanced Squamous Cell Carcinoma of the Esophagus (NEOCRTEC5010): A Phase III Multicenter, Randomized, Open-Label Clinical Trial.
Not available
S-EPMC6145832 | biostudies-literature
Proteomicsyagwall_712rpt
enrichment for Halobacterium cell wall proteins; 700-1200 m/z; Goo et al., unpublished data.
ORGANISM(S): Halobacterium Nrc-1 (halobacterium) 
2006-12-31 | PAe000225 | PeptideAtlas
ProteomicsPhosphoproteomics reveal that phosphorylation of MTDH by CDK5 inhibits protein synthesis in microglia
Our findings identified 335 phosphorylation sites on 234 proteins as potential CDK5 substrates in microglia based on the reported sequence motif
ORGANISM(S): Mus Musculus 
2024-03-08 | PXD050465 |
ProteomicsTargeting NADPH oxidase and integrin α5β1 to inhibit neutrophil extracellular traps-mediated metastasis in colorectal cancer
Using multiple mass spectrometry-based proteomic approaches, our results comprehensively elucidate the entire process by which increased NETs accelerate tumor progression.
ORGANISM(S): Homo Sapiens 
2023-10-27 | PXD046490 |
ProteomicsProteomic landscape of serum exosomes to identify potential therapeutic targets.
Using a tandem mass tag (TMT)-based quantitative proteomics approach, we characterized the proteomes of individual patient-derived serum exosomes, identified exosomal protein signatures specific to TNBC patients, and filtered out differentially expressed proteins.
ORGANISM(S): Homo Sapiens 
2021-08-04 | PXD027696 |
Proteomicslysine succinylation files of different freezability Mediterranean buffalo sperms.
For the first time this study provides lysine succinylation files of different freezability Mediterranean buffalo sperms.
ORGANISM(S): Bubalus Bubalis 
2021-11-29 | PXD030051 |
ProteomicsTargeting high circDNA2v levels in colorectal cancer induces cellular senescence and elicits an anti-tumor secretome
The efficacy of immunotherapy against colorectal cancer (CRC) is impaired by insufficient immune cell recruitment into the tumor microenvironment. Our study shows that targeting circDNA2v, a circular RNA commonly overexpressed in CRC, can be exploited to elicit cytotoxic T-cell recruitment. CircDNA2...
ORGANISM(S): Homo Sapiens 
2024-04-11 | PXD051359 |
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