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UnknownEnhancement of tunability of MAPK cascade due to coexistence of processive and distributive phosphorylation mechanisms.
Not available
S-EPMC4026786 | biostudies-literature
TranscriptomicsPredict cytogenetic abnormalities with gene expression profiles
Cytogenetic abnormalities (CA) are important clinical parameters in various types of cancer, including multiple myeloma (MM). We developed a model to predict CA in patients with MM using gene expression profiling (GEP) and validated it by different cytogenetic techniques. The model was shown to have...
ORGANISM(S): Homo sapiens 
2012-06-11 | E-GEOD-29023 | biostudies-arrayexpress
ProteomicsQuantitative Determination of Strontium Ion (Sr2+) Release Kinetics from Sr-containing Metal-Organic Frameworks via ICP-MS
This project provides a comprehensive dataset of Strontium ion (Sr2+) release profiles from Sr-containing metal-organic frameworks (Sr/MOF). Using Inductively Coupled Plasma Mass Spectrometry (ICP-MS), we quantitatively analyzed the ion release kinetics over a 21-day period to evaluate the material'...
ORGANISM(S): Synthetic Construct (code 6) 
2026-04-20 | PXD077411 |
ProteomicsInteractome of FLAG-STING in HCT116 cell line with or without P. gingivalis infection
The project aims to identify STING interactome that affected by P. gingivalis infection in HCT116 cells.
ORGANISM(S): Homo Sapiens 
2025-09-18 | PXD068516 |
ProteomicsProteomics profile of large extracellular vesicles derived from P. gingivalis–infected HCT116 cells
HCT116 cells were treated with/without P. gingivalis for 48h, then the large extracellular vesicles (lEV) were isolated via a series of differential centrifugation steps. then the purified lEVs were used for label free quantitative proteomics analysis. Three biological replicates are prepared for ea...
ORGANISM(S): Homo Sapiens 
2025-01-17 | PXD059913 |
ProteomicsDiscovery of Novel MLKL PROTAC Degrader for the Treatment of Hepatocellular Carcinoma via Promoting Parthanatos
Chen et al. discovered a highly potent and selective MLKL-targeted PROTAC C116 that effectively induces MLKL degradation and promotes parthanatos in HCC cells. More significantly, C116 was able to induce in vivo MLKL degradation and exerts anti-tumor activities in an orthotopic HCC tumor model, posi...
ORGANISM(S): Mus Musculus 
2025-10-14 | PXD069462 |
ProteomicsMass-spectroscopic quantification of CHAC1-regulated protein cysteine S-glutathionylation
S-glutathionylation is an important post-translational modification of a cysteine residue of target protein. We applied a quantitative redox proteomics approach to identify the specific cysteine residues as targets of S-glutathionylation. Using this approach, we profiled CHAC1-associated changes in ...
ORGANISM(S): Mus Musculus 
2024-03-12 | PXD050569 |
ProteomicsInsight of novel biomarkers for papillary thyroid carcinoma through multi-omics
Our multi-omics analysis of local patients demonstrated significant distinctions compared to TCGA-THCA cohorts, highlighting the unique genetic characteristics of Chinese individuals with PTC. We identified novel biomarkers that hold potential for diagnosis and prognosis of PTC. Furthermore, develop...
ORGANISM(S): Homo Sapiens 
2023-08-23 | PXD044815 |
ProteomicsIntegrative proteomic characterization of human lung adenocarcinoma
Genomic studies of lung adenocarcinoma (LUAD) have advanced understanding of the disease’s biology and accelerated targeted therapy. However, proteomic characteristics of LUAD remain poorly understood. We carried out comprehensive proteomic analysis of 103 cases of LUAD in Chinese patients. Integrat...
ORGANISM(S): Homo Sapiens 
2020-07-10 | PXD020252 |
UnknownRobust estimation of bacterial cell count from optical density.
Not available
S-EPMC7499192 | biostudies-literature
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