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Tea plants (Camellia sinensis) present an excellent system to study evolution and diversification of specialized metabolites due to their abundance in classes, numbers and contents. A large number of tea cultivars have been cultivated throughout the world not only because of their adaption to differ...
2020-10-05 | MTBLS1405 | MetaboLights
Traditional Chinese medicines (TCM), usually composed of a mixture of components, may simultaneously target multiple genes/pathways and thus achieve superior efficacy for complex diseases such as cancer. To identify novel mechanisms of action and potential health benefits for a TCM formula Si-Wu-Tan...
ORGANISM(S): Homo sapiens 
Hepatocellular carcinoma (HCC) is frequently characterized by metabolic and immune remodeling in the tumor microenvironment. We previously discovered that liver-specific deletion of fructose-1, 6-bisphphotase 1 (FBP1), a gluconeogenic enzyme ubiquitously suppressed in HCC tissues, promotes liver tum...
ORGANISM(S): Homo sapiens (Human) 
2023-03-11 | PXD026822 | Pride
Transcriptome sequencing of Foxtail millet Setaria italica (Zhang-gu) for different tissues. Four RNA pools were created corresponding to four different tissues: root, leaf, stem, spica (tassel) at developmental stage, then each pool was sequenced.
ORGANISM(S): Setaria italica 
Hypoxic pre-conditioning has been demonstrated to increase the resistance of neural stem cells (NSCs) to hypoxic conditions, as well as to improve their capacity for differentiation and neuro-genesis. Extracellular vesicles (EVs) have recently emerged as critical mediators of cell-cell com-municatio...
ORGANISM(S): Mus Musculus 
2022-11-07 | PXD037966 |
The vector tick Haemaphysalis longicornis exhibits two reproductive strategies: bisexual populations (HLBP) and parthenogenetic populations (HLPP). To understand the molecular function of genes associated with H. longicornis ovarian development, an integration of quantitative proteomics was carried...
ORGANISM(S): Haemaphysalis Longicornis 
2021-11-01 | PXD029485 |
The protein binding with diabetes induced circulation associated circular RNA (DICAR) pf db/db mouse compared with wild type
ORGANISM(S): Mus Musculus 
We examined fecal proteins from normal subjects (n=6), patients with inflammatory bowel disease (n=8), patients with colorectal adenoma (n=8), and patients with colorectal cancer (n=14) in the hope of identifying novel fecal protein markers that could be used to identify colorectal diseases.
ORGANISM(S): Homo Sapiens 
2022-12-22 | PXD039089 |
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