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UnknownThe phenotypic characteristics of polymorphonuclear neutrophils and their correlation with B cell and CD4+T cell subsets in thyroid-associated ophthalmopathy.
Not available
S-EPMC11371595 | biostudies-literature
ProteomicsViral control by a unique cytotoxic SARS-CoV-2 spike protein-specific CD4+ T cell population
Little is known of the role of cytotoxic CD4+ T-cells (CTLs) in the control of human viral replication. Here, we investigate CD4+ T-cell responses to three immunodominant SARS-CoV-2 epitopes identified in our study cohort, and evaluate cytotoxic activity and antiviral cytokine production in response...
ORGANISM(S): Severe acute respiratory syndrome coronavirus 2 Homo sapiens (Human) 
2025-08-15 | PXD042469 | Pride
Human Epitotpes Sars-cov-2 Cd4+ tcells Lc-ms/ns 
ProteomicsA Universal 384-Well Proteomic Sample Preparation Platform for High-Throughput Screening and Biomarker Discovery
Major advances have been made to develop an automated universal 384-well plate sample preparation platform with high reproducibility and adaptability for extraction of proteins from cells within a culture plate. An in-solution digest strategy is employed to generate peptides from the extracted prote...
ORGANISM(S): Homo sapiens (Human) 
2021-06-14 | PXD019733 | Pride
Proteomics Hplc-ms Mrm High-throughput screening Biomarkers 
ProteomicsA Universal 384-Well Proteomic Sample Preparation Platform for High-Throughput Screening and Biomarker Discovery
Major advances have been made to improve the sensitivity of mass analyzers, spectral quality, and the speed of data processing enabling more comprehensive proteome discovery and quantitation. While focus has recently begun shifting toward robust proteomic sample preparation efforts, a high throughpu...
ORGANISM(S): Homo sapiens (Human) 
2021-06-14 | PXD023374 | Pride
High-throughput Hplc-ms/ms Proteomics Biomarker Compound screen 
UnknownDifferentially expressed genes in orbital adipose/connective tissue of thyroid-associated orbitopathy.
Not available
S-EPMC10734407 | biostudies-literature
ProteomicsA small molecule VDAC ligand inhibits ERAD and induces selective cancer cell death via disruption of calcium homeostasis
Endoplasmic reticulum-associated degradation (ERAD) is a critical protein quality control mechanism that also regulates lipid metabolism and calcium homeostasis. Dysregulation of ERAD and unfolded protein response underlies diseases including cancer, neurodegenerative disorders, and metabolic syndro...
ORGANISM(S): Homo sapiens (Human) 
2026-01-20 | PXD071546 | Pride
Erad Proteomics Ingel digestion Er-phagy Vdac 
UnknownProtein catenation potentiates antitumor activity of malaria VAR2CSA navigation CAR-T cells in a mouse model of hematological malignancies.
Not available
S-EPMC12636975 | biostudies-literature
UnknownSuppression of 4.1R enhances the potency of NKG2D-CAR T cells against pancreatic carcinoma via activating ERK signaling pathway.
Not available
S-EPMC8455638 | biostudies-literature
UnknownCo-Expression of IL-7 Improves NKG2D-Based CAR T Cell Therapy on Prostate Cancer by Enhancing the Expansion and Inhibiting the Apoptosis and Exhaustion.
Not available
S-EPMC7409228 | biostudies-literature
UnknownCD19-CAR-T Cells Bearing a KIR/PD-1-Based Inhibitory CAR Eradicate CD19+HLA-C1- Malignant B Cells While Sparing CD19+HLA-C1+ Healthy B Cells.
Not available
S-EPMC7564565 | biostudies-literature
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