Sort   by:  
 Page size 
TranscriptomicsIdentification of miRNAs which bind to YB-1 protein
To assess the direct association of the nucleic acid binding protein yb-1 with mature microRNAs in breast cancer. To do this we performed immunoprecipitation (IP) of YB-1 protein to pull-down linked RNAs Two breast cancer cell-lines, representative of Luminal A and Basal molecular subtypes were used...
ORGANISM(S): Homo sapiens 
2014-01-23 | E-GEOD-50141 | biostudies-arrayexpress
TranscriptomicsEffects of YB-1 protein reduction on microRNA abundance in breast cancer cell-lines
To assess the association of the nucleic acid binding protein yb-1 with mature microRNAs levels in breast cancer. To do this we performed YB-1 siRNA treatement in triplicates alongside an siRNA control Two breast cancer cell-lines, representative of Luminal A and Basal molecular subtypes were used, ...
ORGANISM(S): Homo sapiens 
2014-01-23 | E-GEOD-50087 | biostudies-arrayexpress
TranscriptomicsMechanism and transcriptional program of YB-1 in breast cancer cell lines.
YB-1 controls epithelial-mesenchymal transitions by restricting translation of growth-related mRNAs and enabling expression of EMT-inducing transcription factors. We used microarrays to characterize the direct transcriptional and indirect translational regulation of mRNAs by exogenous YB-1 in breast...
ORGANISM(S): Homo sapiens 
2008-10-30 | E-GEOD-13410 | biostudies-arrayexpress
ProteomicsClass I HDAC inhibitors enhance YB-1 acetylation and oxidative stress to block sarcoma metastasis
Outcomes for metastatic bone sarcomas, Ewing sarcoma and osteosarcoma, are dismal and remain unchanged for decades. Oxidative stress attenuates melanoma metastasis, and melanoma cells must reduce oxidative stress to metastasize. To explore this in sarcomas, we screened libraries of approved compound...
ORGANISM(S): Homo sapiens (Human) 
2019-10-28 | PXD014827 | Pride
Yb-1 Ms275 Sarcoma Hdac 
GenomicsTranscriptome (RNA-Seq), translatome (Ribo-Seq), and YB-1/YB-3-bound mRNAs (RIP-Seq) of HEK293T, HEK293TdeltaYB-1, and HEK293T+HA-YB-1 cells
Transcriptome (RNA-Seq), translatome (Ribo-Seq), and YB-1/YB-3-bound mRNAs (RIP-Seq) of HEK293T, HEK293TdeltaYB-1, and HEK293T+HA-YB-1 cells
PRJNA541324 | ENA
TranscriptomicsLinks between the Oncoprotein YB-1 and Small Non-Coding RNAs in Breast Cancer
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Homo sapiens 
2014-01-23 | E-GEOD-50142 | biostudies-arrayexpress
TranscriptomicsTranscriptome (RNA-Seq), translatome (Ribo-Seq), and YB-1/YB-3-bound mRNAs (RIP-Seq) of HEK293T, HEK293TdeltaYB-1, and HEK293T+HA-YB-1 cells
We present results of RNA-Seq, Ribo-Seq, and RIP-Seq (YB-1, YB-3) experiments performed in HEK293T cells, as well as in HEK293T cells with YB-1 knockout and overexpression. The data shows YB-1 function as a global translation inhibitor and YB-3 ability to substitute YB-1 in its function in YB-1 knoc...
ORGANISM(S): Homo sapiens 
2020-01-08 | GSE130781 | GEO
GenomicsChanges in transcriptome and translatome upon YB-1 or YB-3 expression in double knockout HEK293T ΔYB-1ΔYB-3 cells
Changes in transcriptome and translatome upon YB-1 or YB-3 expression in double knockout HEK293T ΔYB-1ΔYB-3 cells
PRJNA1051101 | ENA
GenomicsYB-1 inhibits proliferation of mesothelioma cells through multiple mechanisms
YB-1 inhibits proliferation of mesothelioma cells through multiple mechanisms
PRJNA642157 | ENA
GenomicsPAR-CLIP analysis of YB-1 RNA binding in HEK293T cells
PAR-CLIP analysis of YB-1 RNA binding in HEK293T cells
PRJNA1051100 | ENA
Sort   by:  
 Page size