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MetabolomicsUncovering the Complexity of the Yeast Lipidome by Means of nLC/NSI-MS/MS
Saccharomyces cerevisiae is a eukaryotic model organism widely used for the investigation of fundamental cellular processes and disease mechanisms. Consequently, the lipid landscape of yeast has been extensively investigated and up to this day the lipidome is considered as rather basic. Here, we use...
2021-01-08 | MTBLS2119 | MetaboLights
TranscriptomicsCPD-seq mapping of UV damage formation and repair in yeast
UV-induced DNA lesions are an important contributor to mutagenesis and cancer, but it is not fully understood how the chromosomal landscape influences UV lesion formation and repair. We have used a novel high-throughput sequencing method to precisely map UV-induced cyclobutane pyrimidine dimers (CPD...
ORGANISM(S): Saccharomyces cerevisiae 
2016-08-19 | E-GEOD-79977 | biostudies-arrayexpress
ProteomicsNanodiscs-based proteomics to identify lipid-interacting proteins in yeast
Many soluble proteins interact with membranes to perform important biological functions, including signal transduction, regulation, transport, trafficking and biogenesis. Despite their importance, these protein-membrane interactions are difficult to characterize due to their often-transient nature a...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2021-12-30 | PXD027992 | Pride
Hsp40 Caj1 Silac labeling Nanodiscs Rab gtpase 
TranscriptomicsCell cycle- and chaperone-mediated regulation of H3K56ac incorporation in yeast
Acetylation of histone H3 lysine 56 is a covalent modification best-known as a mark of newly-replicated chromatin, but has also been linked to replication-independent histone replacement. Here, we measured H3K56ac levels at single-nucleosome resolution in asynchronously growing yeast cultures, as w...
ORGANISM(S): Saccharomyces cerevisiae 
2008-10-03 | E-GEOD-12822 | biostudies-arrayexpress
UnknownProteomic and genomic characterization of a yeast model for Ogden syndrome.
Not available
S-EPMC5248646 | biostudies-literature
TranscriptomicsDietary folate depletion and repletion in A/J and C57BL/6J mice
Defects in homocysteine and folate metabolism are associated with increased risks for neural tube and congenital heart defects, cardiovascular disease and stroke, cancers, and neurodegeneration. In many but not all cases, dietary supplementation with folate significantly reduces the severity and in...
ORGANISM(S): Mus musculus 
2008-08-27 | E-GEOD-9242 | biostudies-arrayexpress
UnknownRibosomal DNA sequence heterogeneity reflects intraspecies phylogenies and predicts genome structure in two contrasting yeast species.
Not available
S-EPMC4055870 | biostudies-literature
UnknownUse of a fluoride channel as a new selection marker for fission yeast plasmids and application to fast genome editing with CRISPR/Cas9.
Not available
S-EPMC5363073 | biostudies-literature
TranscriptomicsTranscription profiling of yeast recovery after hydrogen peroxide stress
Yeast cells response during recovery after hydrogen peroxide stress. Comparison of yeast cells treated with 1.5mM hydrogen peroxide for 30 min with cells allowed to recover for 60 min
ORGANISM(S): Saccharomyces cerevisiae 
2006-01-28 | E-MEXP-326 | biostudies-arrayexpress
TranscriptomicsRNA Polymerase mapping during stress responses reveals widespread nonproductive transcription in yeast
The use of genome-wide RNA abundance profiling by microarrays and deep sequencing has spurred a revolution in our understanding of transcriptional control. However, changes in mRNA abundance reflect the combined effect of changes in RNA production, processing, and degradation, and thus, mRNA levels ...
ORGANISM(S): Saccharomyces cerevisiae 
2010-07-16 | E-GEOD-22675 | biostudies-arrayexpress
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