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MetabolomicsThe putative ceramide-conjugation protein Cwh43 regulates G0 quiescence, nutrient metabolism and lipid homeostasis in fission yeast (Metabolome assay)
Cellular nutrient states control whether cells proliferate, or whether they enter or exit quiescence. Here, we report characterizations of fission yeast temperature-sensitive (ts) mutants of the evolutionarily conserved transmembrane protein, Cwh43, and explore its relevance to utilization of glucos...
2018-08-17 | MTBLS577 | MetaboLights
MetabolomicsThe putative ceramide-conjugation protein Cwh43 regulates G0 quiescence, nutrient metabolism and lipid homeostasis in fission yeast (Lipidome assay)
Cellular nutrient states control whether cells proliferate, or whether they enter or exit quiescence. Here, we report characterizations of fission yeast temperature-sensitive (ts) mutants of the evolutionarily conserved transmembrane protein, Cwh43, and explore its relevance to utilization of glucos...
2018-08-21 | MTBLS578 | MetaboLights
ProteomicsA conserved signaling network monitors delivery of sphingolipids to the plasma membrane in budding yeast.
48 total runs: three biological replicates, 8 runs each, each run as technical duplicates
ORGANISM(S): Saccharomyces Cerevisiae (ncbitaxon:4932) 
2017-04-13 | MSV000080919 | MassIVE
MetabolomicsThe Impacts of Sortase A and the 4'-Phosphopantetheinyl Transferase Homolog Sfp on Streptococcus mutans Extracellular Membrane Vesicle Biogenesis

Extracellular membrane vesicles (EMVs) are produced by many Gram-positive organisms, but information regarding vesiculogenesis is incomplete. We used single gene deletions to evaluate the impacts on Streptococcus mutans EMV biogenesis of Sortase A (SrtA), which affects S. mutans...

2021-10-06 | MTBLS1812 | MetaboLights
TranscriptomicsYeast Membrane Bound Polysome
Set of arrays organized by shared biological context, such as organism, tumors types, processes, etc. mRNA species bound to membrane-associated polysomes were separated from other mRNAs by sedimentation equilibrium or sedimentation velocity. The distribution of individual transcripts in the 'membran...
ORGANISM(S): Saccharomyces cerevisiae 
2005-08-24 | E-GEOD-3180 | biostudies-arrayexpress
TranscriptomicsCharacterization of human plasma-derived exosomal RNAs
Exosomes, endosome-derived membrane microvesicles, contain a specific set of RNA transcripts that are involved in cell-cell communication and hold a great potential as disease biomarkers. To systemically characterize exosomal RNA profiles, we performed RNA sequencing analysis using three human plasm...
ORGANISM(S): Homo sapiens 
2013-05-15 | E-GEOD-45722 | biostudies-arrayexpress
ProteomicsSTUDY OF THE PLASMA MEMBRANE PROTEOME DYNAMICS REVEALS NOVEL TARGETS OF THE NITROGEN REGULATION IN YEAST
Yeast cells, to be able to grow on a wide variety of nitrogen sources, regulate the set of nitrogen transporters present at their plasma membrane. Such regulation relies on both transcriptional and post-translational events. While large-scale microarray studies have identified most nitrogen-sensitiv...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2017-07-10 | PXD005273 | Pride
Yeast plasma membrane Proteomics Transporters Nitrogen sources Endocytosis Arrestin 
TranscriptomicsProfiling the transcriptional response upon deletion of PUN1
Yeast filamentous growth is a stress response to conditions of nitrogen deprivation, wherein yeast colonies form pseudohyphal filaments of elongated and connected cells. As proteins mediating adhesion and transport are required for this growth transition, the protein complement at the yeast cell pe...
ORGANISM(S): Saccharomyces cerevisiae 
2010-02-17 | E-GEOD-20351 | biostudies-arrayexpress
TranscriptomicsIncrease in membrane cholesterol of neurons in culture recapitulates AlzheimerM-bM-^@M-^Ys disease early phenotypes.
Levels of membrane-associated cholesterol were shown to be increased in the brain of individuals with sporadic AlzheimerM-bM-^@M-^Ys disease (AD) and correlated with the severity of the disease. We previously found that heavy membrane cholesterol burden promotes amyloid precursor protein (APP) endoc...
ORGANISM(S): Rattus norvegicus 
2015-01-15 | E-GEOD-46221 | biostudies-arrayexpress
ProteomicsVAP-mediated membrane tethering mechanisms implicate ER-PM contact function in pH homeostasis
MS analyses of interactome of full-length (i.e., Scs2 and Scs22) and TM-truncated (i.e., Scs2N and Scs22N) fission yeast VAPs.
ORGANISM(S): Schizosaccharomyces Pombe (fission Yeast) 
2024-08-09 | PXD053887 | JPOST Repository
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