Transcriptional profiling was performed on cells grown in YEPD medium at 28 M-0C to an OD600 nm = 1.8, in case of cells grown in exponential phase; alternatively, cells were growth in 1% N-acetylglucosamine and 50 mM citrate buffer pH6.0 at 28 M-0C for different times points (15, 60 and 180 minutes)...
The polymorphic yeast Candida albicans exists in blastospore and filamentous forms. The switch from one morphological state to the other coincides with the expression of virulence factors, which makes the yeast-to-hypha transition an attractive target for the development of new antifungal agents. Be...
Recent studies have shown that the transcriptional landscape of the pleiomorphic fungus Candida albicans is highly dependent upon growth conditions. Here using a dual RNA-seq approach we identified 299 C. albicans and 72 Streptococcus gordonii genes that were either up- or down-regulated specificall...