Sort   by:  
 Page size 
MetabolomicsImpact of acute lymphoblastic leukemia induction therapy: findings from metabolomics on non-fasted plasma samples from a biorepository

INTRODUCTION: Acute lymphoblastic leukemia (ALL) is among the most common cancers in children. With improvements in combination chemotherapy regimens, the overall survival has increased to over 90%. However, the current challenge is to mitigate adverse events resulting from the c...

2021-08-12 | MTBLS2394 | MetaboLights
ProteomicsSystematic Proteomics Revealed The mechanism of How Long-term Tibetan Buddhist Meditation Enhanced Cardiovascular Protection
The difficulty to obtain data from whom uninterruptedly practice meditation over many years, and lacking of advanced analysis methods significantly hinder the comprehensive understanding of molecular mechanisms underlying meditation. This study aimed to address this issue.Accordingly, we recruited 8...
ORGANISM(S): Homo Sapiens 
2018-09-27 | PXD057418 |
TranscriptomicsExpression data from Arabidopsis thaliana root protoplast
BACKGROUND:Dynamic transcriptional regulation is critical for an organism's response to environmental signals and yet remains elusive to capture. Such transcriptional regulation is mediated by master transcription factors (TF) that control large gene regulatory networks. Recently, we described a dyn...
ORGANISM(S): Arabidopsis thaliana 
2016-02-08 | E-GEOD-69389 | biostudies-arrayexpress
TranscriptomicsGene profiling of v-Src transformed primary chicken cells
Cell transformation by the Src tyrosine kinase is characterized by extensive changes in gene expression. To describe these changes, investigators have relied extensively on the study of immortalized rodent cell lines or heterogeneous tumor samples that limit the identification of differentially exp...
ORGANISM(S): Gallus gallus 
2010-02-21 | E-GEOD-14489 | biostudies-arrayexpress
UnknownN(6)-methyladenosine-binding protein YTHDF1 suppresses EBV replication and promotes EBV RNA decay
Not available
S-SCDT-EMBOR-2020-50128V1 | biostudies-other
ProteomicsMudPIT LiPMS analyses of whole cell protein extracts from Saccharomyces cerevisiae grown at 21C and 35C
Sample Preparation. Three biological replicates of wild type yeast cells (BY4741) were cultured with YEPD either at 21C or 35C overnight (ca. 18hrs) to OD600 around 2. Pre-warmed/chilled fresh YEPD was next used to dilute the cultures, which were grown for an additional 6hrs to OD600 around 1. 120m...
ORGANISM(S): Saccharomyces Cerevisiae (ncbitaxon:4932) 
2021-02-01 | MSV000086790 | MassIVE
UnknownEstimating the sample mean and standard deviation from commonly reported quantiles in meta-analysis.
Not available
S-EPMC7390706 | biostudies-literature
ProteomicsQuantitative In Vivo Proteomics of Metformin Response in Liver Reveals AMPK-Dependent and -Independent Signaling Networks
Metformin is the front-line treatment for type 2 diabetes worldwide. It acts via effects on glucose and lipid metabolism in metabolic tissues, leading to enhanced insulin sensitivity. Despite significant effort, the molecular basis for metformin response remains poorly understood, with a limited nu...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2019-10-07 | MSV000084429 | MassIVE
TranscriptomicsGenome-wide analysis of alternative splicing in Caenorhabditis elegans
Alternative splicing (AS) plays a crucial role in the diversification of gene function and regulation. Consequently, the systematic identification and characterization of temporally regulated splice variants is of critical importance to understanding animal development. We have used high-throughput ...
ORGANISM(S): Caenorhabditis elegans 
2010-12-14 | E-GEOD-25927 | biostudies-arrayexpress
ProteomicsDependency of NELF-E-KAT2B epigenetic axis in breast cancer carcinogenesis
Cancer cells undergo transcriptional reprogramming to drive tumor progression and metastasis. Here, we identified the transcriptional complex, NELF (Negative elongation factor), as an important regulator of this process. Using cancer cell lines and patient-derived tumor organoids, we demonstrated th...
ORGANISM(S): Homo Sapiens (human) 
2023-01-28 | PXD031304 | JPOST Repository
Sort   by:  
 Page size