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ProteomicsProteome analysis in the TcMAC21 mouse model of Down syndrome
Down syndrome (DS) results from trisomy of human chromosome 21 (HSA21), and DS research has been greatly advanced by the use of mouse models. We previously generated a humanized mouse model of DS, TcMAC21, which carries the long arm of HSA21. These mice exhibit learning and memory deficits, and may ...
ORGANISM(S): Mus musculus (Mouse) 
2023-10-23 | PXD044343 | Pride
Lc-msms Down syndrome Phospho-proteome Tcmac21 
ProteomicsMouse Circadian Proteome Atlas by next-generation deep proteome analysis
The circadian clock drives daily rhythms of gene expression and physiological functions across tissues throughout the body. Advances in next-generation DNA sequencing have provided extensive insights into gene expression at the RNA level, but more functional information at the protein level with suf...
ORGANISM(S): Mus musculus (Mouse) 
2025-11-27 | PXD064534 | Pride
Proteomics Circadian 
ProteomicsMouse Circadian Proteome Atlas by next-generation deep proteome analysis
The circadian clock drives daily rhythms of gene expression and physiological functions across tissues throughout the body. Advances in next-generation DNA sequencing have provided extensive insights into gene expression at the RNA level, but more functional information at the protein level with suf...
ORGANISM(S): Mus musculus (Mouse) 
2025-11-27 | PXD064539 | Pride
Circadian Mouse Proteome 
ProteomicsMouse Circadian Proteome Atlas by next-generation deep proteome analysis
The circadian clock drives daily rhythms of gene expression and physiological functions across tissues throughout the body. Advances in next-generation DNA sequencing have provided extensive insights into gene expression at the RNA level, but more functional information at the protein level with suf...
ORGANISM(S): Mus musculus (Mouse) 
2025-11-27 | PXD064583 | Pride
Circadian Mouse Proteome 
ProteomicsMouse Circadian Proteome Atlas by next-generation deep proteome analysis
The circadian clock drives daily rhythms of gene expression and physiological functions across tissues throughout the body. Advances in next-generation DNA sequencing have provided extensive insights into gene expression at the RNA level, but more functional information at the protein level with suf...
ORGANISM(S): Mus musculus (Mouse) 
2025-11-27 | PXD064461 | Pride
Mouse Circadian Proteomics 
ProteomicsMouse Circadian Proteome Atlas by next-generation deep proteome analysis
The circadian clock drives daily rhythms of gene expression and physiological functions across tissues throughout the body. Advances in next-generation DNA sequencing have provided extensive insights into gene expression at the RNA level, but more functional information at the protein level with suf...
ORGANISM(S): Mus musculus (Mouse) 
2025-11-27 | PXD061981 | Pride
ProteomicsMouse Circadian Proteome Atlas by next-generation deep proteome analysis
The circadian clock drives daily rhythms of gene expression and physiological functions across tissues throughout the body. Advances in next-generation DNA sequencing have provided extensive insights into gene expression at the RNA level, but more functional information at the protein level with suf...
ORGANISM(S): Mus musculus (Mouse) 
2025-11-27 | PXD069823 | Pride
Proteome analysis Phosphorylation Circadian clock 
ProteomicsMouse Circadian Proteome Atlas by next-generation deep proteome analysis
The circadian clock drives daily rhythms of gene expression and physiological functions across tissues throughout the body. Advances in next-generation DNA sequencing have provided extensive insights into gene expression at the RNA level, but more functional information at the protein level with suf...
ORGANISM(S): Mus musculus (Mouse) 
2025-11-27 | PXD069794 | Pride
Orbitrap astral Circadian Phosphorylation 
ProteomicsTRAF7 determines circadian period through ubiquitination and degradation of DBP
D-site binding protein, DBP, is a clock-controlled transcription factor and drives daily rhythms of physiological processes through the regulation of an array of genes harboring a DNA binding motif, D-box. DBP protein levels show a circadian oscillation with an extremely robust peak/trough ratio, bu...
ORGANISM(S): Mus musculus (Mouse) 
2024-08-28 | PXD051884 | Pride
Traf7 Ubiquitination Protein degradation Circadian clock Dbp 
ProteomicsAbe_et_al_Nature_Communications_2022_mass_spectrometry_rawdata
This is supplemental raw data for Abe et al., 2022. Proteome analysis and phospho-proteome analysis using mouse liver prepared at 6 circadian time points (CT2, 6, 10, 14, 18, 22). In the delta-RRE mutant, two RRE sequences are removed from 5'UTR of mouse Bmal1 gene.
ORGANISM(S): Mus musculus (Mouse) 
2022-07-20 | PXD035414 | Pride
Mouse liver lc-msms 
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