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Transgenic KrasG12D mice can recapitulate pancreas intra-epithelial neoplasia (PanIN). Caerulein is a cholecystokinin analogue and induces acute pancreatitis when injected intra-abdominally. Caerulein-induced acute pancreatitis will accelerate PanIN progression in KrasG12D mice. We compared mRNA pro...
ORGANISM(S): Mus musculus 
Hyocholic acid (HCA) is a major bile acid (BA) species in the BA pool of pigs, a species known for its exceptional resistance to spontaneous development of diabetic phenotypes. HCA and its derivatives are also present in human blood and urine. We investigate whether human HCA profiles can predict th...
2021-10-06 | MTBLS2343 | MetaboLights
Efficient biotechnological conversion of lignocellulosic biomass to valuable products, such as transportation biofuels, is ecologically attractive, yet requires substantially improved mechanistic understanding and optimization to become economically feasible. Cellulolytic clostridia, such as Ruminic...
ORGANISM(S): [Clostridium] papyrosolvens DSM 2782 
2019-11-11 | PXD013253 | Pride
Our studies reveal that S100A16 overexpression triggers GC cells proliferation and migration both in vivo and in vitro; by contrast, S100A16 knockdown restricts the speed of GC cells growth and mobility. Proteomic analysis results reveal a large S100A16 interactome, which includes ZO-2 (Zonula Occlu...
ORGANISM(S): Homo sapiens (Human) 
2022-02-17 | PXD028022 | Pride
Paired serological proteomes from CHB patients undergoing short-term and long-term anti-viral treatment were profiled using 4D-DIA-based proteomics technology.The serological proteomic landscapes following AVT were systematically analyzed and compared between fibrosis regressors and non-regressors.
ORGANISM(S): Homo sapiens (Human) 
2025-08-25 | PXD059174 | Pride
Paired serological proteomes from CHB patients undergoing short-term and long-term anti-viral treatment were profiled using PRM-based proteomics technology.The serological proteomic landscapes following AVT were systematically analyzed and compared between fibrosis regressors and non-regressors.
ORGANISM(S): Homo sapiens (Human) 
2025-08-25 | PXD063833 | Pride
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