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TranscriptomicsChronic alcohol consumption from adolescence-to-adulthood in mice M-bM-^@M-^T Effect on gene expression in the hypothalamus
We employed a paradigm of chronic moderate alcohol intake from adolescence-to-adulthood in mice, and analyzed the alcohol effect on both behavioral and hypothalamic gene expression changes. We employed a paradigm of chronic moderate alcohol intake from adolescence-to-adulthood in mice. Before chroni...
ORGANISM(S): Mus musculus 
2013-06-30 | E-GEOD-42770 | biostudies-arrayexpress
TranscriptomicsTranscriptional analysis of luxS-null strain in Yersinia pestis CO92 at 37M-BM-0C
Yersinia pestis, the etiological agent of plague, is able to sense cell density by quorum sensing. The function of quorum sensing in Y. pestis is not clear. Here, the process of autoinducer 2 (AI-2) quorum sensing was investigated by comparing transcript profiles when luxS gene was knocked out. The ...
ORGANISM(S): Yersinia pestis 
2013-09-05 | E-GEOD-22849 | biostudies-arrayexpress
TranscriptomicsGenome-wide copy number variant analysis in inbred lines of chickens with different susceptibility to MarekM-bM-^@M-^Ys disease
MarekM-bM-^@M-^Ys disease virus (MDV) is an oncovirus causing tumor disease known as MarekM-bM-^@M-^Ys disease (MD) in chicken. Breeding of chickens genetically resistant to MD is considered a vital augment to better control MD. To find the mechanism underlying the genetic resistance to MD, a genomi...
ORGANISM(S): Gallus gallus 
2012-09-01 | E-GEOD-38689 | biostudies-arrayexpress
TranscriptomicsTranscriptional analysis of quorum sensing deficient in Yersinia pestis CO92 at 37M-BM-0C
Yersinia pestis, the etiological agent of plague, is able to sense cell density by quorum sensing. The function of quorum sensing in Y. pestis is not clear. Here, the process of quorum sensing was investigated by comparing transcript profiles when three quorum-sensing synthase genes are knocked out....
ORGANISM(S): Yersinia pestis 
2013-09-05 | E-GEOD-21911 | biostudies-arrayexpress
TranscriptomicsTissue-enriched expression profiles in Aedes aegypti identify hemocyte-specific transcriptome responses to infection
We present a microarray study of hemocyte-enriched transcriptome in Aedes aegypti. We directed our efforts to critically assess the transcriptomic features distinctive of hemocytes, and discussed our findings in relation to infection-responsive genes and immune-relate gene families. Specifically, ou...
ORGANISM(S): Aedes aegypti 
2012-07-22 | E-GEOD-38744 | biostudies-arrayexpress
TranscriptomicsA genome-wide transcriptome analysis reveals diverse roles of two-component system DraR-K in physiological and morphological differentiation of Streptomyces coelicolor
A novel two-component system (TCS) DraR-K was identified previously to play a differential role in antibiotic biosynthesis (ACT, RED and yCPK) of Streptomyces coelicolor M145 on defined minimal medium (MM) conditions. In order to assess whether DraR-K has more global roles, a genome-wide transcripto...
ORGANISM(S): Streptomyces coelicolor 
2014-03-10 | E-GEOD-55714 | biostudies-arrayexpress
TranscriptomicsSperm but not oocyte DNA methylome is inherited by zebrafish early embyros
5-methylcytosine is a major epigenetic modification sometimes called "the fifth nucleotide". However, our knowledge of how offspring inherit the DNA methylome from parents is limited. We generated nine single-base resolution DNA methylomes including zebrafish gametes and early embryos. The...
ORGANISM(S): Danio rerio 
2013-05-20 | E-GEOD-44075 | biostudies-arrayexpress
TranscriptomicsTranscriptional analysis of three quorum sensing signals add in experiment inYersinia pestis CO92 at 37M-BM-0C
Yersinia pestis, the etiological agent of plague, is able to sense cell density by quorum sensing. The function of quorum sensing in Y. pestis is not clear. Here, the process of quorum sensing was investigated by comparing transcript profiles when three quorum-sensing signals are added in. The strai...
ORGANISM(S): Yersinia pestis 
2013-09-05 | E-GEOD-22846 | biostudies-arrayexpress
TranscriptomicsTranscription analysis of AI-2 signal add in experiment in Yersinia pestis CO92 at 37M-BM-0C
Yersinia pestis, the etiological agent of plague, is able to sense cell density by quorum sensing. The function of quorum sensing in Y. pestis is not clear. Here, the process of autoinducer-2 (AI-2) quorum sensing was investigated by comparing transcript profiles when AI-2 quorum-sensing signal is a...
ORGANISM(S): Yersinia pestis 
2013-09-05 | E-GEOD-22848 | biostudies-arrayexpress
GenomicsTet and TDG Mediate DNA Demethylation Essential for MET in Somatic Cell Reprogramming
Tet-mediated DNA oxidation is a new type of epigenetic modification in mammals and its role in the regulation of cell fate transition remains poorly understood. Here, we derive mouse embryonic fibroblasts (MEFs) deleted in all three Tet genes and examine their capability to be reprogrammed into iPS ...
ORGANISM(S): Mus musculus 
2014-02-19 | E-GEOD-52741 | biostudies-arrayexpress
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