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MetabolomicsMulti-omics integration reveals Yu-Xue-Bi tablets attenuate rheumatoid arthritis via metabolic reprogramming-mediated Piezo1 suppression

As a systemic chronic inflammatory disease, Rheumatoid arthritis (RA) is characterized by progressive inflammation, bone and cartilage destruction, leading to significant disability, reduced lifespan, and increased mortality. The clinical use of conventional medications including nonsteroidal ant...

2026-01-24 | MTBLS13760 | MetaboLights
TranscriptomicsA genome-wide transcriptome analysis reveals diverse roles of two-component system DraR-K in physiological and morphological differentiation of Streptomyces coelicolor
A novel two-component system (TCS) DraR-K was identified previously to play a differential role in antibiotic biosynthesis (ACT, RED and yCPK) of Streptomyces coelicolor M145 on defined minimal medium (MM) conditions. In order to assess whether DraR-K has more global roles, a genome-wide transcripto...
ORGANISM(S): Streptomyces coelicolor 
2014-03-10 | E-GEOD-55714 | biostudies-arrayexpress
ProteomicsIP-MS identification of protein interaction for Na (+), K (+)-ATPase beta1 subunit
This project aims to identify proteins that may interact with the sodium potassium pump (ATPase) beta1 subunit in the human lung.
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2020-02-02 | MSV000084881 | MassIVE
UnknownRosiglitazone selectively inhibits K(ATP) channels by acting on the K(IR) 6 subunit.
Not available
S-EPMC3448911 | biostudies-literature
UnknownProtonation of key acidic residues is critical for the K⁺-selectivity of the Na/K pump.
Not available
S-EPMC3190665 | biostudies-literature
ProteomicsUbiquitin-mediated modulation of necroptotic effector MLKL
We aimed to identify lysine (K) residues that are endogenously ubiquitylated upon TNF-induced necroptosis. To this end, we used a quantitative mass spectrometry-based approach. Briefly, MDFs were treated with TSZ or left untreated and protein lysates were digested with trypsin into peptides. Ubiquit...
ORGANISM(S): Mus musculus (Mouse) 
2021-04-13 | PXD018857 | Pride
Ubiquitin Tmt Cancer Mlkl Mouse Msms 
Unknown*K-means and cluster models for cancer signatures.
Not available
S-EPMC5634820 | biostudies-literature
UnknownK-Profiles: A Nonlinear Clustering Method for Pattern Detection in High Dimensional Data.
Not available
S-EPMC4538770 | biostudies-literature
UnknownThe 164 K, 165 K, and 167 K residues of VP1 are vital for goose parvovirus proliferation in GEFs based on PCR-based reverse genetics system.
Not available
S-EPMC6854815 | biostudies-literature
UnknownHuman endogenous retrovirus K (HERV-K) envelope structures in pre- and postfusion by cryo-EM.
Not available
S-EPMC12383274 | biostudies-literature
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