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MetabolomicsThe trans-omics landscape of COVID-19
The outbreak of coronavirus disease 2019 (COVID-19) is a global health emergency. Various omics results have been reported for COVID-19, but the molecular hallmarks of COVID-19, especially in those patients without comorbidities, have not been fully investigated. Here we collect blood samples from 2...
2021-10-06 | MTBLS2542 | MetaboLights
ProteomicsRepurposing Lusutrombopag: Unveiling Anti-Staphylococcus aureus Activity in a Novel Oral Thrombopoietin Receptor Agonist
Here are the findings from the DARTs (Drug Affinity Responsive Target Stability) and proteomics studies for Lusutrombopag
ORGANISM(S): Staphylococcus Aureus Subsp. Aureus Nctc 8325 
2025-12-17 | PXD072172 |
ProteomicsMLS0315771 S. aureus YUSA145 proteomics
Quantitative label-free proteomic analysis investigated the global proteomic response of S. aureus YUSA145 treated with 1/2 × MIC MLS0315771 during the exponential growth phase. The results were obtained after performing principal component analysis (PCA) on the raw data and excluding two replicates...
ORGANISM(S): Staphylococcus Aureus 
2026-01-24 | PXD073535 |
ProteomicsComparison of the significantly differentially expressed protein between K2044, K2044-8Xyl-60G, K2044-ΔXylA and K2044-ΔXylB treated with 8% xylose
The K. pneumoniae K2044, K2044-8Xyl-60G, K2044-ΔXylA and K2044-ΔXylB isolates were cultured overnight in MRS medium, then 1:200 diluted in MRS medium with 8% xylose to reach the exponential growth phase. The control group was K2044 treated with 8% xylose. The experiment was performed in triplicate.
ORGANISM(S): Klebsiella Pneumoniae 1191100241 
2024-11-04 | PXD057506 |
ProteomicsNovel SLCO2B1 mRNA isoform acts as a noncoding RNA and drives cancer progression through FMR1-mediated protein biosynthesis
The eukaryotic 5’ untranslated region (5’ UTR) canonically influences mRNA translation efficiency. However, the role of the 5’ UTR structure in blocking mRNA translation and turning a coding RNA into a noncoding RNA remains undocumented. Herein, we discovered a novel mRNA isoform of the human solute...
ORGANISM(S): Homo Sapiens 
2025-11-27 | PXD071347 |
ProteomicsHSP60-mediated UPRmt overactivation drives triptolide-induced Hepatocellular lipoapoptosis
This study aims to investigate the role of excessive activation of the mitochondrial unfolded protein response (UPRmt) in TP-induced liver injury and to elucidate the mechanism by which HSP60 mediates this process in regulating lipid metabolism disorders.
ORGANISM(S): Mus Musculus 
2026-01-08 | PXD072797 |
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