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ProteomicsIn-cell proteomics enables high-resolution temporal profiling of cell cycle progression and DNA damage response in Saccharomyces cerevisiae
Yeast is a widely used model organism in biological and proteomics research. Conventional bottom-up proteomic analysis of yeast cells requires disruption of the rigid cell wall to extract proteins, which is often associated with lengthy procedures, significant technical variations and noticeable sam...
ORGANISM(S): Saccharomyces Cerevisiae (ncbitaxon:4932) 
2025-05-26 | MSV000097997 | MassIVE
ProteomicsBenchmarking In-Cell Proteomics For Profiling Neuroblastoma Cell Differentiation And The Ubiquitin-Proteasome System
The human neuroblastoma SH-SY5Y cell line is a widely utilized model for studying neurodegenerative diseases, owing to its ability to differentiate into cells with a neuron-like phenotype. However, a comprehensive understanding of the cellular and molecular mechanisms underpinning the SH-SY5Y cell d...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2025-05-02 | MSV000097787 | MassIVE
ProteomicsSaccharomyces cerevisiae LC-MSMS
Multi-omics Elucidation of Resource Allocation for Enhanced Ethanol Production via Precise Glucose Control in Anaerobic Saccharomyces cerevisiae Fermentation
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2025-12-08 | PXD068901 | Pride
Saccharomyces cerevisiae lc-msms 
ProteomicsDegrade BTK and GSPT1 Proteins Concurrently
GBD-9 chemically induce the degradation of BTK and GSPT1 by merging the PROTAC and MG strategies.
ORGANISM(S): Homo Sapiens 
2021-04-25 | PXD025609 |
ProteomicsBCL7A and BCL7B potentiate SWI/SNF-complex-mediated chromatin accessibility to regulate gene expression and vegetative phase transition in Arabidopsis
Arabidopsis thaliana, 14-day-old seedlings grow in 1/2 MS culture medium under short day condition, LC-MS. In this project, two different materials (One is in the wild type background, the other is in the mutant background.) were used to do CoIP experiments, and then mass spectrometry was carried ou...
ORGANISM(S): Arabidopsis Thaliana 
2024-01-03 | PXD045757 |
ProteomicsOrganization, genomic targeting and assembly of three distinct SWI/SNF chromatin remodeling complexes in Arabidopsis
To comprehensively define the potential plant SWI/SNF sub-complexes and their subunits organization, we started by performing immuno-purification followed by mass spectrometry analysis (IP-MS) using stable transgenic Arabidopsis lines that expressed a green fluorescent protein (GFP)-tagged ATPase su...
ORGANISM(S): Arabidopsis Thaliana 
2023-04-15 | PXD041567 |
ProteomicsProteomic profiling of the global protein changes of Neuro-2a cells treated with dFUS-E9C or control
We conducted unbiased mass spectrometric experiments to evaluate the specificity of dFUS-E9C. In these studies, Neuro-2a cells were treated with dFUS-E9C. The result revealed the detection of more than 5000 proteins, among which there was a notable degradation of FUS, confirming the targeted action ...
ORGANISM(S): Mus Musculus 
2025-04-04 | PXD062671 |
ProteomicsProteomic profiling of the global protein changes of Neuro-2a cells treated with siFUS or control
We conducted unbiased mass spectrometric experiments to evaluate the specificity of siFUS. In these studies, Neuro-2a cells were treated with siFUS. The result revealed the detection of more than 5000 proteins, among which there was a notable degradation of FUS, confirming the targeted action of siF...
ORGANISM(S): Mus Musculus 
2025-04-07 | PXD062670 |
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