In this study, differential genes and proteins in cryptorchidism and normal testis were screened by high-throughput transcriptome sequencing (RNA-seq) and tmt-based proteomics techniques, and the potential factors of cryptorchidism were analyzed.
Proteomic analysis of Ago2-/- oocytes revealed that Ago2 interacted with endogenous small interfering RNAs (endo-siRNAs) to repress mRNA translation globally.
