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UnknownPercolation Phase Transition of Surface Air Temperature Networks: A new test bed for El Nino/La Nina simulations.
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S-EPMC5559492 | biostudies-literature
TranscriptomicsNext generation sequencing of Desulfovibrio vulgaris Hildenborough in the presence of Free Nitrous Acid stress
Purpose: Free nitrous acid (FNA) has recently been demonstrated as an antimicrobial agent to a range of microorganisms. However, its antimicrobial mechanism is largely unknown. For this study Desulfovibrio vulgaris Hildenborough was selected to gain a systematic understanding of the antimicrobial me...
ORGANISM(S): Desulfovibrio vulgaris 
2016-07-01 | E-GEOD-78834 | biostudies-arrayexpress
TranscriptomicsRNA-seq analysis of flg22-induced gene expression changes in wild type, asr3-1 mutant and OX9 overexpression line
The correlation coefficient (R) for the expression profile of all transcripts between WT and asr3-1, and between WT and OX9 without flg22 treatment is close to linear, suggesting that ASR3 does not affect general gene transcription. Hierarchical clustering analysis flg22-induced genes in any of the ...
ORGANISM(S): Arabidopsis thaliana 
2015-08-26 | E-GEOD-63603 | biostudies-arrayexpress
TranscriptomicsLncRNAs expression profiles in the livers of 20-month-old male HBx transgenic mice and C57BL/6 wild-type mice
The hepatitis B virus X protein (HBx) has been implicated as an oncogene in both epigenetic modifications and genetic regulation during hepatocarcinogenesis, but the underlying mechanisms are not entirely clear. Long non-coding RNAs (lncRNAs), which regulate gene expression with little or no protein...
ORGANISM(S): Mus musculus 
2013-11-04 | E-GEOD-42185 | biostudies-arrayexpress
TranscriptomicsmRNA expression in blood of 18 schizophrenia patients and 12 healthy controls
The study profiles genome-wide mRNA expression in blood from 18 early-onset SZ (EOS) cases and 12 healthy controls. A total of 1070 mRNAs were detected by the microarrays in our samples. 18 schizophrenia samples and 12 healthy controls were used to acquire blood expression profiles
ORGANISM(S): Homo sapiens 
2014-12-05 | E-GEOD-54913 | biostudies-arrayexpress
GenomicsPaternally induced transgenerational inheritance of susceptibility to diabetes in mammals (MeDIP-Seq)
The global prevalence of type 2 diabetes (T2D) is increasing, and it is contributing to the susceptibility to diabetes and its related epidemic in offspring. Although the impacts of paternal T2D on metabolism of offspring have been well established, the exact molecular and mechanistic basis that med...
ORGANISM(S): Mus musculus 
2013-01-02 | E-GEOD-43238 | biostudies-arrayexpress
GenomicsChromatin states in the Arabidopsis shoot apical meristem
We investigated the chromatin modifications H3K4me3 and H3K27me3 in the A. thaliana shoot apical meristem using INTACT reporter lines. Samples were collected in two biological replications.
ORGANISM(S): Arabidopsis thaliana 
2017-05-21 | E-MTAB-4684 | biostudies-arrayexpress
GenomicsChromatin states in the Arabidopsis seedlings
We investigated the chromatin modifications H3K4me3 and H3K27me3 in the A. thaliana seedlings. Samples were collected in two biological replications.
ORGANISM(S): Arabidopsis thaliana 
2017-05-21 | E-MTAB-4680 | biostudies-arrayexpress
GenomicsH3K4me3 and H3K27me3 chromatin states in the Arabidopsis shoot phloem companion cells from INTACT reporter lines
We investigated the chromatin modifications H3K4me3 and H3K27me3 in the A. thaliana shoot phloem companion cells using INTACT reporter lines. Samples were collected in two biological replications.
ORGANISM(S): Arabidopsis thaliana 
2019-01-09 | E-MTAB-5737 | biostudies-arrayexpress
GenomicsEZH2 inhibitor efficacy in non-Hodgkin lymphoma does not require suppression of H3K27 mono-methylation [ChIP-Seq]
Here we report the discovery of highly potent and selective EZH2 small molecule inhibitors, their validation by a cellular thermal shift assay, their application across a large lymphoma cell panel and their efficacy in GCBDLBCL xenograft models. Baseline ChIP-seq measurement of KARPAS-422 cell line ...
ORGANISM(S): Homo sapiens 
2015-04-13 | E-GEOD-62057 | biostudies-arrayexpress
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