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UnknownMagnetic resonance imaging (MRI) of perianal granular cell tumor: A case report and literature review.
Granular cell tumor (GCT) is a rare soft tissue neoplasm. At present, there is limited information available on the incidence, diagnosis, and treatment of GCTs. Therefore, we perform magnetic resonance imaging (MRI) of a perianal GCT case and review the literature of other reported cases to obtain a...
S-EPMC6584453 | biostudies-literature
UnknownHepatic hydrothorax in the absence of ascites with mixed bacterial and fungal infection: a case report.

Background

Hepatic hydrothorax (HH) is a rare complication of cirrhosis, typically caused by the transdiaphragmatic migration of ascitic fluid. However, HH can also occur without ascites, complicating both diagnosis and treatment. Infections in HH, particularly with pathogens such as Enteroc...
S-EPMC12512935 | biostudies-literature
UnknownPrior culture-guided prediction of antibiotic susceptibility in recurrent respiratory tract infections: a retrospective cohort analysis.

Background

Recurrent respiratory tract infections (RRTIs) are a serious problem in older adults, necessitating appropriate early empiric antibiotic therapy. However, rising antimicrobial resistance complicates empiric treatment selection. Although prior culture results can offer guidance for...
S-EPMC12816384 | biostudies-literature
UnknownPROS1 is a crucial gene in the macrophage efferocytosis of diabetic foot ulcers: a concerted analytical approach through the prisms of computer analysis.

Background

Diabetic foot ulcers (DFUs) pose a serious long-term threat because of elevated mortality and disability risks. Research on its biomarkers is still, however, very limited. In this paper, we have effectively identified biomarkers linked with macrophage excretion in diabetic foot ul...
S-EPMC11087110 | biostudies-literature
UnknownEffects of Tanreqing injection on the gut microbiota in healthy volunteers.

Objectives

Many studies have confirmed that antibacterial agents can disrupt the human gut microbiota. In China, Tanreqing injection (TRQ) is a drug with antibacterial activity that is widely used in the treatment of respiratory infections. However, its specific influence on gut microbiota r...
S-EPMC11486765 | biostudies-literature
UnknownHollow CuS nanocubes enhance serum metabolic profiles for rapid diagnosis and severity grading of traumatic brain injury.
Traumatic brain injury (TBI) remains a significant global health burden and demands rapid, objective diagnostics that work outside imaging suites and intensive lab workflows. Here, we developed a copper sulfide (CuS) nanocube-assisted laser desorption/ionization mass spectrometry (LDI-MS) platform t...
S-EPMC12702368 | biostudies-literature
UnknownMultiplex nucleotide editing by high-fidelity Cas9 variants with improved efficiency in rice.

Background

Application of the CRISPR/Cas9 system or its derived base editors enables targeted genome modification, thereby providing a programmable tool to exploit gene functions and to improve crop traits.

Results

We report that PmCDA1 is much more efficient than rAPOBEC1 when fused ...
S-EPMC6873407 | biostudies-literature
UnknownThe relationship between respiratory symptoms and frailty: findings from observational and Mendelian randomization analyses.

Introduction

As ageing accelerates, frailty increasingly impacts public health. Cough, sputum, wheezing and dyspnea are common respiratory symptoms, and the relationship to frailty is unclear. We aimed to analyze the relationship between respiratory symptoms and frailty.

Methods

Cross...
S-EPMC11685262 | biostudies-literature
UnknownEffects of perioperative transcutaneous electrical acupoint stimulation on monocytic HLA-DR expression in patients undergoing coronary artery bypass grafting with cardiopulmonary bypass: study protocol for a double-blind randomized controlled trial.

Background

Cardiac surgery involving cardiopulmonary bypass (CPB) is known to be associated with a transient postoperative immunosuppression. When severe and persistent, this immune dysfunction predisposes patients to infectious complications, which contributes to a prolonged stay in the int...
S-EPMC6937832 | biostudies-literature
UnknownHigh-risk adverse events in two types of single inhaler triple-therapy: a pharmacovigilance study based on the FAERS database.

Objective

Single inhaler triple therapy is widely used in Chronic Obstructive Pulmonary Disease (COPD) and asthma. This research aimed to analyze adverse events (AEs) associated with Budesonide/Glycopyrronium/Formoterol Fumarate (BUD/GLY/FOR) and Fluticasone Furoate/Umeclidinium/Vilanterol (...
S-EPMC11754260 | biostudies-literature
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