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ProteomicsChromatin profiling in human neurons reveals aberrant roles for histone acetylation and BET family proteins in schizophrenia
Schizophrenia (SZ) is a psychiatric disorder with complex genetic risk dictated by interactions between hundreds of risk variants. Epigenetic factors, such as histone posttranslational modifications (PTMs), have been shown to play critical roles in many neurodevelopmental processes, and when perturb...
ORGANISM(S): Homo sapiens (Human) 
2022-05-06 | PXD031767 | Pride
Bet proteins Mass spectrometry Histone modifications Schizophrenia Rna-seq 
ProteomicsIntegrated Multi-Omics Reveal Polycomb Repressive Complex 2 Restricts Human Trophoblast Induction
Human naive pluripotent stem cells have unrestricted lineage potential. Underpinning this property, naive cells are thought to lack chromatin-based lineage barriers. However, this assumption has not been tested. Here, we define the chromatin-associated proteome, histone post-translational modificati...
ORGANISM(S): Homo sapiens (Human) 
2022-05-09 | PXD032792 | Pride
H3k27me3 Trophoblast fate Polycomb repressive complex 2 (prc2) Chromatin proteomes Human pluripotent stem cells 
UnknownAn efficient screening system of disease-resistant genes from wild apple, Malus sieversii in response to Valsa mali pathogenic fungus.
Not available
S-EPMC10693133 | biostudies-literature
UnknownAssociation of Inpatient Use of Angiotensin-Converting Enzyme Inhibitors and Angiotensin II Receptor Blockers With Mortality Among Patients With Hypertension Hospitalized With COVID-19.
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S-EPMC7265882 | biostudies-literature
UnknownRemapping the spatial distribution of neutralizing sites and their immunodominance on the capsid of different topotypes of FMDV serotype O by site-directed competitive ELISA for detection of neutralizing antibodies.
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S-EPMC12131818 | biostudies-literature
UnknownRedefining Cardiac Biomarkers in Predicting Mortality of Inpatients With COVID-19.
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S-EPMC7375179 | biostudies-literature
UnknownEndocrine Regulator rFGF21 (Recombinant Human Fibroblast Growth Factor 21) Improves Neurological Outcomes Following Focal Ischemic Stroke of Type 2 Diabetes Mellitus Male Mice.
Not available
S-EPMC6310061 | biostudies-literature
UnknownIncontinentia Pigmenti: A Case Report of Early Clinical Symptoms in a Lack of Family Inheritance Positive Result.
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S-EPMC10182818 | biostudies-literature
UnknownEvaluating the mosquito vector range for two orthobunyaviruses: Oya virus and Ebinur Lake virus.
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S-EPMC11077878 | biostudies-literature
Unknown(-)- and (+)-Securidanes A and B, Natural Triarylmethane Enantiomers: Structure and Bioinspired Total Synthesis.
Not available
S-EPMC6750104 | biostudies-literature
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