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ProteomicsViperin Mediates Coxsackievirus B3-induced Acute Heart Failure via KCNQ1 Ion Channel
Given that CVB3 is able to impair myocardial contractility, which finally leads to acute heart failure (AHF) and even sudden death, we tried to analyze the related myocardial function of these groups of mice
ORGANISM(S): Mus musculus (Mouse) 
2025-05-06 | PXD036898 | Pride
Viperin  cvb3  acute heart failure  sgk1 
ProteomicsProteomics coupled transcriptomics reveals lipopolysaccharide inhibiting peroxisome proliferator-activated receptors signalling pathway to reduce lipid droplets accumulation in mouse liver
Lipid droplets (LDs) are multifunctional organelles consisting of a central compartment of non-polar lipids shielded from the cytoplasm by a phospholipid monolayer. The excessive accumulation of lipid droplets in cells is closely related to the development and progression of many diseases in humans ...
ORGANISM(S): Mus Musculus 
2023-01-27 | PXD039724 |
ProteomicsThe Dynll1-Cox4il Complex Regulates Intracellular Pathogen Clearance via Release of Mitochondrial Reactive Oxygen Species
Cellular membrane proteins are a critical part of the host defense mechanisms against infection and intracellular survival of Listeria monocytogenes. The complex spatiotemporal regulation of bacterial infection by various membrane proteins has been challenging to study. Here, using mass spectrometry...
ORGANISM(S): Mus Musculus 
2020-02-17 | PXD016452 |
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