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Effective silencing by RNA-interference (RNAi) depends on mechanisms that amplify and propagate the silencing signal. In some organisms, small-interfering (si) RNAs are amplified from target mRNAs by RNA-dependent RNA polymerase (RdRP). Both RdRP recruitment and mRNA silencing require Argonaute prot...
ORGANISM(S): Caenorhabditis elegans 
Bulk RNA-Seq of muscle isolated from zebrafish carrying a mutation in telomerase (tert) and wildtype sibling animals aged 5 days at 24 hpf following needle stick injury. RNA was extracted from pooled samples of n=50 larvae each on 30/01/2024. Libraries were constructed using Illumina TruSeq RNA Libr...
ORGANISM(S): Danio rerio 
Undifferentiated cells of different passage numbers (p19 and p128) were compared to cells differentiated in hanging drops for 5 days (d5 embryoid bodies) or expanded on gelatin coated dishes for a further 9 days (d14 embryoid bodies).
ORGANISM(S): Homo sapiens 

Seed development dedicates to reserve synthesis and accumulation and uncovering its genetic and biochemical mechanisms has been a major research focus. Although proteomic and transcriptomic analyses revealed dynamic changes of genes and enzymes involved, the information regarding concomitant meta...

2016-05-03 | MTBLS288 | MetaboLights
We discovered that cellular uptake of sorbate, an FDA-approved and widely used food preservative, can induce lysine sorbylation (Ksor), a new posttranslational modification and epigenetic mark. Proteomics analysis identified over 20 histone sorbylation sites in cells and mouse liver as well as over ...
ORGANISM(S): Homo sapiens (Human) Mus musculus (Mouse) 
2025-04-22 | PXD058007 | Pride
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