Sort   by:  
 Page size 
ZAR1 is an RNA binding protein and mediated the homeostasis of maternal transcriptome in oocytes as a component of mitochondria-associated ribonucleoprotein domain (MARDO). Here, we identified the ZAR1 interactive proteins in mouse oocytes.
ORGANISM(S): Mus musculus (Mouse) 
2025-03-11 | PXD055584 | Pride
ZAR1/2-regulated Histone Modifications are Required for Zygotic Activation and Age-associated Oocyte Quality Maintenance
ZAR1 and ZAR2 are Required for Oocyte Meiotic Maturation by Regulating the Maternal Transcriptome and mRNA Translational Activation
Zar1 was the first mammalian maternal-effect gene to be identified. Embryos derived from Zar1-null female mice are blocked before zygotic genome activation; however, the underlying mechanism remains unclear. By knocking out Zar1 and its homolog Zar2 in mice, we revealed a novel function of these gen...
ORGANISM(S): Mus musculus 
2019-09-25 | GSE135787 | GEO
The developmental competence and epigenetic progression of oocytes gradually become dysregulated with increasing maternal age. However, the mechanisms underlying age-related epigenetic regulation in oocytes remain poorly understood. Zygote arrest proteins 1 and 2 (ZAR1/2) are two maternal factors wi...
ORGANISM(S): Mus musculus 
2025-03-05 | GSE275156 | GEO
Sort   by:  
 Page size