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MetabolomicsMyocardial-intrinsic defects underlie an Rbfox-mediated zebrafish model of hypoplastic left heart syndrome
Hypoplastic left heart syndrome (HLHS) is characterized by underdevelopment of left sided structures including the ventricle, valves, and aorta1. Although the mechanisms of disease pathogenesis remain elusive due to a paucity of candidate genes and animal models, prevailing paradigm suggests that HL...
2022-07-12 | MTBLS4176 | MetaboLights
MetabolomicsMetabolomic profiling of zebrafish DSS-induced colitis intervened by Akkermansia muciniphila-derived extracellular vesicles (AmEVs)
This study performs untargeted metabolomics analysis on intestinal tissues of DSS-induced colitis zebrafish models to uncover the metabolic regulatory mechanisms of AmEVs. We compared intestinal metabolite profiles between two experimental groups: DSS-induced colitis model group and AmEV interventio...
2026-07-22 | MTBLS14855 | MetaboLights
MetabolomicsMetabolomic Responses to Circadian Rhythm Disruption in Zebrafish

Circadian rhythms are essential biological oscillators that synchronize physiological processes, cellular homeostasis, and systemic metabolism with the Earth's natural 24-hour light-dark cycle. While circadian rhythm disruption (CRD) is highly prevalent in modern society due to factors such as sh...

2026-06-23 | MTBLS14815 | MetaboLights
MetabolomicsZebrafish Metabolomics: Model for Environmental Metal Toxicity
Not available
ORGANISM(S): Danio rerio 
ST000365 | MetabolomicsWorkbench
TranscriptomicsTranscriptomic analyses of Myc-induced zebrafish liver cancer
To study the characteristics and mechanisms of Myc-induced zebrafish liver tumor, next-generation sequencing-based SAGE analyses were used to examine the transcriptomes of tumor and control samples. The results indicated that ribosome proteins were overwhelmingly up-regulated in the Myc-induced live...
ORGANISM(S): Danio rerio 
2013-04-02 | E-GEOD-40745 | biostudies-arrayexpress
TranscriptomicsAdult zebrafish: cornea vs dermis
Transcriptional profiling of adult zebrafish cornea against dermis as a reference. Three biological repeats with dye swap (6 chips of 1x22k for 6 data sets).
ORGANISM(S): Danio rerio 
2015-02-19 | E-GEOD-24593 | biostudies-arrayexpress
ProteomicsZebrafish embryo_phosphorylation_18O labeling
The zebrafish (Danio rerio) is a popular animal model in studies of vertebrate development and organogenesis. Recent research has shown a similarity of approximately 70% between the human and zebrafish genomes and of 84% in human disease-causing genes, specifically. Zebrafish embryos have a number o...
ORGANISM(S): Danio rerio (Zebrafish) (Brachydanio rerio) 
2015-10-14 | PXD002232 | Pride
: zebrafish embryo 18o labeling Global phosphoproteome 
TranscriptomicsAdult zebrafish: cornea vs epidermis
Transcriptional profiling of adult zebrafish cornea against epidermis as a reference. Four biological repeats with dye swap (2 chips of 4x44k for 8 data sets).
ORGANISM(S): Danio rerio 
2015-02-19 | E-GEOD-24595 | biostudies-arrayexpress
TranscriptomicsSystematic Transcriptome Analysis of Zebrafish Model of Diamond-Blackfan Anemia from RPS24 Deficiency (mRNA-Seq)
In this study, we found RPS24 is required for both the primitive hematopoiesis and definitive hematopoiesis process partly mediated by P53 pathway. With the RNA-seq and miRNA-seq technique, several deregulated genes and miRNAs were found to be related with hematopoiesis, vascular development and apo...
ORGANISM(S): Danio rerio 
2015-05-18 | E-GEOD-54152 | biostudies-arrayexpress
TranscriptomicsSystematic Transcriptome Analysis of Zebrafish Model of Diamond-Blackfan Anemia from RPS24 Deficiency (miRNA-Seq)
In this study, we found RPS24 is required for both the primitive hematopoiesis and definitive hematopoiesis process partly mediated by P53 pathway. With the RNA-seq and miRNA-seq technique, several deregulated genes and miRNAs were found to be related with hematopoiesis, vascular development and apo...
ORGANISM(S): Danio rerio 
2015-05-18 | E-GEOD-54259 | biostudies-arrayexpress
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