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The segmented pattern of the vertebral column and musculature in vertebrate embryos is established during somitogenesis. Here, using the model animal zebrafish, we employed Data-Independent Acquisition (DIA) to capture the proteomics change at the early stages of somite development.
ORGANISM(S): Danio rerio (Zebrafish) (Brachydanio rerio) 
2025-10-13 | PXD058516 | Pride
Integrins are a major class of heterodimeric adhesion receptors composed of an a and b subunit that mediate cell adhesion to the extracellular matrix (ECM). The extracellular matrix protein fibronectin is important for early vertebrate development, and Integrin a5b1 and aVb3 are the two primary fibr...
ORGANISM(S): Danio rerio (Zebrafish) (Brachydanio rerio) 
2021-09-10 | PXD024665 | Pride
Differentially expressed genes along the paraxial mesoderm of 12 somite stage zebrafish embryos are identified Tissue samples from 6 different spatial positions were dissected from wild-type (AB) embryos, RNA is amplified and hybridized to arrays
ORGANISM(S): Danio rerio 
Investigation of whole genome gene expression level changes in zebrafish TIF1g-deficient, cdc73 deficient and double-deficient embryos, compared to the wild-type ebryos. A twelve-chip study using total RNA isolated from gata1-GFP positive cells (sorted by FACS) from 12 somite-stage wild type embryos...
ORGANISM(S): Danio rerio 
ATAC-seq profile of zebrafish periderm at 4-somite stage
mRNA profile of zebrafish periderm at 4-somite stage
Delta-like 3 (Dll3) is a divergent ligand and modulator of the Notch signaling pathway only identified so far in mammals. Null mutations of Dll3 disrupt cycling expression of Notch targets Hes1, Hes5, and Lfng, but not of Hes7. Compared with Dll1 or Notch1, the effects of Dll3 mutations are less se...
ORGANISM(S): Mus musculus 
Transcriptome analysis during embryogenesis usually requires pooling of embryos to obtain sufficient RNA. Hence, the measured levels of gene-expression represent the average mRNA levels of pooled samples and the biological variation among individuals is lost for inclusion into statistical models use...
ORGANISM(S): Danio rerio 
We integrate zebrafish embryology with photoactivatable caged morpholinos (cMO), the photoactivatable lineage tracer caged fluorescein-dextran (cFD), fluorescence-activated cell-sorting (FACS) and RNA sequencing (RNA-seq) to identify Spadetail-regulated genes in mesodermal cells enriched for early s...
ORGANISM(S): Danio rerio 
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