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UnknownAntigen-Specificity of T Cell Infiltrates in Biopsies With T Cell-Mediated Rejection and BK Polyomavirus Viremia: Analysis by Next Generation Sequencing.
Not available
S-EPMC5083170 | biostudies-literature
ProteomicsAMBRA1 controls the translation of immune-specific genes in T lymphocytes
T cell receptor (TCR) engagement causes a global cellular response that entrains signaling pathways, cell cycle regulation, and cell death. The molecular regulation of mRNA translation in these processes is poorly understood. During a whole-genome CRISPR screen for regulators of CD95 (Fas/APO-1)-med...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2024-10-08 | MSV000096042 | MassIVE
TranscriptomicsSingle cell RNA seq of influenza tetramer specific CD8+ T cells from baseline, acute and long term memory timepoints
The aim of the experiment was to assess the differentiation and activation status of influenza-specific CD8+ T cells (A2/PB1 413 and A2/BHA 543) from an individual naturally infected with influenza B (PCR-confirmed). Single tetramer+ CD8+ T cells from tetramer-enriched PBMCs were sorted from baselin...
ORGANISM(S): Homo sapiens 
2019-02-18 | E-MTAB-7606 | biostudies-arrayexpress
UnknownmTOR coordinates transcriptional programs and mitochondrial metabolism of activated Treg subsets to protect tissue homeostasis.
Not available
S-EPMC5974344 | biostudies-literature
UnknownNonparametric Maximum Likelihood Estimators of Time-Dependent Accuracy Measures for Survival Outcome Under Two-Stage Sampling Designs.
Not available
S-EPMC6291304 | biostudies-literature
Proteomicsp-FADD-CD8+T cell axis determines hepatocellular carcinoma response to immune checkpoint inhibitors
The heterogenicity of hepatocellular carcinoma (HCC) remains a key obstacle in turning the majority of ‘immune-cold’ tumors ‘hot’ for effective immune checkpoint inhibitors (ICIs). Through analyzing the naturally-existed ‘hot’ HCC variants, we identified fas-associated death domain (FADD) as a key m...
ORGANISM(S): Homo sapiens (Human) 
2025-07-07 | PXD057519 | Pride
Hcc Fadd Hepg2 
UnknownEnhancing chimeric antigen receptor T-cell immunotherapy against cancer using a nanoemulsion-based vaccine targeting cross-presenting dendritic cells.
Not available
S-EPMC7374388 | biostudies-literature
UnknownLow absolute CD4+ T cell counts in peripheral blood: an independent predictor of inferior survival in natural killer/T-cell lymphoma-a retrospective cohort study.
Not available
S-EPMC9652555 | biostudies-literature
UnknownCombined tumor-directed recruitment and protection from immune suppression enable CAR T cell efficacy in solid tumors.
Not available
S-EPMC8189699 | biostudies-literature
UnknownEarly-to-mid stage idiopathic Parkinson's disease shows enhanced cytotoxicity and differentiation in CD8 T-cells in females.
Not available
S-EPMC10662447 | biostudies-literature
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