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TranscriptomicsTranscription profiling of E.coli reveals indole cell signaling occurs primarily at low temperatures in Escherichia coli
We have shown the quorum-sensing signals acylhomoserine lactones (AHLs), autoinducer-2 (AI-2), and indole influence the biofilm formation of Escherichia coli. Here, we investigate how the environment, i.e., temperature, affects indole and AI-2 signaling in E. coli. We show in biofilms that indole a...
ORGANISM(S): Escherichia coli 
2008-06-18 | E-GEOD-9923 | biostudies-arrayexpress
ProteomicsDiscovery of a bifunctional PKMYT1-targeting PROTAC empowered by AI-generation
PKMYT1 has recently emerged as a compelling therapeutic target for precision cancer therapy due to its synthetic lethality with oncogenic alterations such as CCNE1 amplification and mutations in FBXW7 and PPP2R1A. Current small molecule PKMYT1 inhibitors face limitations, such as insufficient molecu...
ORGANISM(S): Homo sapiens (Human) 
2025-09-28 | PXD062889 | Pride
Protac Pkmyt1 Synthetic lethality Ai-generation 
MetabolomicsEffects of Lubabegron Fumarate on Ruminal Fermentation and Microbial Community in a Rumen Simulation System (MS (MTBLS))
Lubabegron fumarate (LBF), a novel β-adrenergic receptor modulator approved to mitigate these emissions, lacks a defined ruminal mode of action. This study aimed to characterise the effects of LBF on in vitro rumen fermentation, microbial ecology, and nitrogen metabolism.
2026-06-12 | MTBLS14756 | MetaboLights
UnknownA Generative AI-Assisted Piezo-MEMS Ultrasound Device for Plant Dehydration Monitoring.
Not available
S-EPMC12407371 | biostudies-literature
UnknownLocal US officials' views on the impacts and governance of AI: Evidence from 2022 and 2023 survey waves.
Not available
S-EPMC12500108 | biostudies-literature
UnknownExploring AI-2-mediated interspecies communications within rumen microbial communities.
Not available
S-EPMC9540692 | biostudies-literature
UnknownDiscovery of a bifunctional PKMYT1-targeting PROTAC empowered by AI-generation.
Not available
S-EPMC12663101 | biostudies-literature
ProteomicsAnalysis of proteins proximal to epsin 1 in A549 cells during entry of influenza A virus
Influenza A viruses (IAVs) are respiratory pathogens that represent a global concern due to their ability to cause seasonal epidemics and sporadic pandemics in the human population. Thus, a comprehensive understanding of IAV biology is essential in order to design effective antivirals. It is well es...
ORGANISM(S): Homo sapiens (Human) Influenza A virus (A/WSN/1933(H1N1)) 
2025-05-08 | PXD058908 | Pride
Epsin 1 Proximity labelling Virus entry Turboid Influenza a virus 
TranscriptomicsProstatic Stromal Cell Gene Expression
We generated prostatic stromal microarray expression data for functional validation of our LOH/AI hot-/cold-spots in stroma. Stromal cells from normal peripheral zone tissue and from tumors are grown in culture, and were analyed on gene expression platform. Stromal cells cultured from normal periphe...
ORGANISM(S): Homo sapiens 
2012-02-27 | E-GEOD-34312 | biostudies-arrayexpress
UnknownCT imaging features of different clinical types of COVID-19 calculated by AI system: a Chinese multicenter study.
Not available
S-EPMC7656439 | biostudies-literature
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