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UnknownNo association between ovarian cancer susceptibility variants and breast cancer risk among Chinese women.
Not available
S-EPMC3596432 | biostudies-literature
TranscriptomicsGenome-wide identification of N6-methyladenosine by microarray
Although internal PolyA RNA modification N6-methyladenosine (m6A) plays essential roles in diverse biological processes, technology to detect precise m6A sites at transcriptome-wide scale is lacking. Here, we discovered that m6A interferes A (Adenine) – U (Uracil) or A-T (Thymidine) pairing. Based o...
ORGANISM(S): Mus musculus 
2015-09-08 | E-GEOD-62530 | biostudies-arrayexpress
UnknownDeciphering the Role of p60AmotL2 in Epithelial Extrusion and Cell Detachment.
Not available
S-EPMC10486482 | biostudies-literature
TranscriptomicsAssociation of genes regulated by Ezh2 and trimethylation of histone 3 lysine 27
Differentiation of naïve CD4+ T cells into effector (Th1, Th2 and Th17) and induced regulatory (iTreg) T cells requires lineage-specifying transcription factors and epigenetic modifications that allow appropriate repression or activation of gene transcription. The epigenetic silencing of cytokine ge...
ORGANISM(S): Mus musculus 
2014-08-04 | E-GEOD-57500 | biostudies-arrayexpress
ProteomicsQuantitative proteomics profiling determines the uniqueness of the sinus node
The sinus node is a collection of highly specialized cells that constitute the natural pacemaker activity of our heart. The protein expression landscape of the sinus node differs from the surrounding cardiac tissue, although it is primarily comprised of myocytes and fibroblasts like the rest of the ...
ORGANISM(S): Mus musculus (Mouse) 
2019-07-08 | PXD008736 | Pride
Pacemaker Heart Tissue Sinus node Mouse Conduction Lc-ms/ms 
ProteomicsRyR2 phosphorylation profile in PKP2cKO mice
The project aimed to investigate whether there are alterations in the phosphorylation status of the Ryanodine receptor 2 (RyR2) in the left atria of mice with a cardiac-specific knockout of PKP2, compared to wild-type mice.
ORGANISM(S): Mus musculus (Mouse) 
2025-10-27 | PXD052074 | Pride
Mouse Immunoprecipitation Ryr2 Phosphorylation 
Proteomicsarrythmogenic right ventricular acrdiomayopathy (PKP2-cko in mice and Human biopsies)
Summary: Arrhythmogenic right ventricular cardiomyopathy (ARVC) is an inherited cardiac disorder. It is classified as the second most common cause of unexpected sudden death by cardiac arrest in the young. ARVC has devastating psychosocial consequences, especially as many patients are young adults, ...
ORGANISM(S): Homo sapiens (Human) Mus musculus (Mouse) 
2022-11-04 | PXD025523 | Pride
Cardiovascular protemics Tmt Heart failure Arvc 
Genomics“Same Difference”: Comprehensive evaluation of four DNA methylation measurement platforms
DNA methylation in CpG context is fundamental to the epigenetic regulation of gene expression in high eukaryotes. Disorganization of methylation status is implicated in many diseases, cellular differentiation, imprinting, and other biological processes. Techniques that enrich for biologically releva...
ORGANISM(S): Homo sapiens 
2016-06-22 | E-GEOD-83595 | biostudies-arrayexpress
TranscriptomicsDNA methylation differences between human regulatory T cells and conventional T cells
Regulatory T cells (Treg) prevent the emergence of autoimmune disease. Prototypic natural Treg (nTreg) are programmed by Forkhead-box P3 (FOXP3) and can be reliably identified by demethylation at the FOXP3 locus. To explore the nTreg methylation landscape we performed genome-wide methylation studies...
ORGANISM(S): Homo sapiens 
2013-09-09 | E-GEOD-49667 | biostudies-arrayexpress
MetabolomicsGNPS_198 root bacteria+interactions
Crude extracts of 198 root-associated bacteria, grown on TSB agar. Additionally, interaction zones of selected bacterial strains were extracted. All file names contain essential information about the sample, first the strain number of the strain collection, then the extraction solvent (E=ethyl aceta...
ORGANISM(S): Root-associated Bacteria 
2017-07-25 | MSV000081381 | GNPS
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