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Formation of biomolecular condensates have emerged as a critical mechanism for compartmentation in living cells. Despite interactions between distinct condensates have been reported, the biological relevance of such interactions remains elusive. In germ cells, small RNA silencing factors are enriche...
ORGANISM(S): Caenorhabditis elegans 
2023-06-16 | PXD037342 | Pride
Germ granules are RNA-rich biomolecular condensates regulating posttranscriptional gene expression. In C. elegans, germ granules are associated with the NPC. Mechanism by which germ granules associate with the nucleus and relevant functions remain unknown. We uncovered the function of the NPP-14/24 ...
ORGANISM(S): Caenorhabditis elegans 
2025-04-14 | PXD051572 | Pride
The ability to distinguish non-self from self is the key characteristic for any defense system. piRNAs function as guardians of the genome by silencing non-self nucleic acids and transposable elements in animals. Many piRNA factors are enriched in perinuclear germ granules, but whether their localiz...
ORGANISM(S): Caenorhabditis elegans 
2022-08-05 | PXD033506 | Pride
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