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TranscriptomicsSmall RNA mediated DNA (cytosine-5) methyltransferase 1 inhibition leads to aberrant DNA methylation
Mammalian cells contain copious amounts of RNA including both coding and non-coding RNA (ncRNA). Generally the ncRNAs function to regulate gene expression at the transcriptional and post-transcriptional level. Among ncRNA, the long ncRNA and small ncRNA can affect histone modification, DNA methylati...
ORGANISM(S): Homo sapiens 
2015-04-21 | E-GEOD-68027 | biostudies-arrayexpress
UnknownTargeting and exploitation of tumor-associated neutrophils to enhance immunotherapy and drug delivery for cancer treatment.
Not available
S-EPMC7142839 | biostudies-literature
ProteomicsQuantitative Proteomics Analysis reveals Proteins related with high melatonin content in barley seeds under NaCl-induced salt stress
Increase soil salinization is affecting hull-less barley cultivation in the Qinghai-Tibet Plateau of China. Under saline conditions wild hull-less barley seeds showed high melatonin (MEL) accumulation during germination with improve salt tolerance. Hence, the present study aimed to understand the pr...
ORGANISM(S): Hordeum Vulgare 
2021-11-29 | PXD030029 |
GenomicsGenome-wide maps of m6dA bases in drosophila ovary genomic DNA
We report the m6dA modification on the Drosophila genome. We collected ovary genomic DNA from 2-day wild-type and DMAD mutant files and performed DNA-immunoprecipitation(DNA-IP)experiments using anti-m6dA antibody. The generated DNA library was subjected to a high-throughput deep sequencing analysis...
ORGANISM(S): Drosophila melanogaster 
2016-06-01 | E-GEOD-64340 | biostudies-arrayexpress
UnknownAGO3 Slicer activity regulates mitochondria–nuage localization of Armitage and piRNA amplification
Not available
S-JCBD-201401002 | bioimages
ProteomicsMulti-omics analysis into the molecular mechanisms underlying the up-regulation of HBG1/2 expression induced by HBB deletion
A multi-omics study examining chromatin accessibility, transcriptome, proteome and phosphorylation patterns in the HBB homozygous knockout of the HUDEP2 cell line (HBB-KO)
ORGANISM(S): Homo sapiens (Human) 
2022-04-04 | PXD030182 | Pride
Omics-study  hbb  hbg1/2  hif1 pathway  stress erythropoiesis 
ProteomicsIdentification of UFBP1 interacting proteins
UFBP1 (UFM1-binding and PCI domain-containing protein 1, also called DDRGK domain-containing protein 1, Dashurin, or C20orf116) is a protein that also participates in the ufmylation conjugating systems besides the E1 ubiquitin-like modifier-activating enzyme 5 (UBA5), the E2, UFM1-conjugating enzyme...
ORGANISM(S): Homo sapiens (Human) 
2018-05-08 | PXD009051 | Pride
293t Interacting proteins Homo sapiens Orbitrap Ufbp1 
ProteomicsMagnetic ConA nanoparticles enriched proteins from urine samples of healthy donors and lung cancer patients
In this project, we used magnetic ConA nanoparticles to purify glycosylated proteins from urine samples of healthy donors and lung cancer patients to discover potential urinary protein biomarker for lung cancer.
ORGANISM(S): Homo sapiens (Human) 
2021-10-12 | PXD025856 | Pride
Human  lung cancer  urine  magnetic cona nanoparticles  lc-ms/ms  orbitrap elite 
UnknownRag2Mol: structure-based drug design based on retrieval augmented generation.
Not available
S-EPMC12159289 | biostudies-literature
ProteomicsQuantitative proteomics identifies myoferlin as a novel regulator of A Disintegrin and Metalloproteinase 12 in HeLa cells
It has been found that A Disintergrin And Metalloproteinase 12 (ADAM12) is significantly higher in multiple tumors and it has been used as a prognostic marker for cancer progression. Several ADAM12 substrates have been identified biochemically and the role of -its proteolytic function has been expl...
ORGANISM(S): Homo sapiens (Human) 
2016-07-21 | PXD003560 | Pride
Adam12 
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