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ProteomicsN-myristoylation by NMT1 is POTEE-dependent to stimulate liver tumorigenesis via differentially regulating ubiquitination of targets
We immuno-precipitated NDP including LXN, RPL29 and FAU, respectively, and NUP including AHSG, ALB and TF, respectively, before setting the immuno-precipitates to the Mass spectrometry (MS).
ORGANISM(S): Homo sapiens (Human) 
2021-09-08 | PXD011906 | Pride
Post-translational modifications (ptms)  n-myristoyltransferase (nmt)  ubiquitin e3 ligase histih4h  proteomics  liver cancer 
ProteomicsiTRAQ experiment to identify proteins that changed before and after NMT1 was knocked down in both Bel-7402 and Bel-7404 cells
We performed proteomics isobaric tags for relative and absolute quantification (iTraq) to identify proteins that changed before and after NMT1 was knocked down in both Bel-7402 and Bel-7404 cells.
ORGANISM(S): Homo sapiens (Human) 
2021-09-08 | PXD011812 | Pride
Itraq，liver cancer，nmt1 knockdown 
ProteomicsDetect the shared protein components between spider dragline silk and silkworm cocoon by Label free quantitative proteomics
The spider major ampullate gland and silkworm silk gland have similar morphological structure and function, so we explored whether there are some common protein components on silks, with three biological replicates for each sample. Dragline silk samples from mature female Trichonephila clavata spide...
ORGANISM(S): Bombyx Mori Trichonephila 
2022-12-09 | PXD038734 |
MetabolomicsLipidomic profiling reveals distinct differences in plasma lipid composition in healthy, prediabetic and type 2 diabetic individuals

The relationship between dyslipidemia and type 2 diabetes mellitus (T2D) has been extensively reported, but the global lipid profiles, especially in the East Asia population, associated with the development of T2D remain to be characterized. Liquid chromatography coupled to tandem mass spectromet...

2017-04-26 | MTBLS352 | MetaboLights
ProteomicsProteomic analysis of supernatant from bone marrow mesenchymal stem cells under high glucose condition
We employed a proteomic analysis to identify proteins with altered expression in the extracellular matrix (ECM), aiming to elucidate the underlying mechanism. 
ORGANISM(S): Homo Sapiens 
2023-11-27 | PXD047253 |
TranscriptomicsTranscriptome analysis of Liangshan pig muscle development at the growth curve inflection point and asymptotic stages using digital gene expression profiling
Animal growth curves can provide essential information for animal breeders to optimize feeding and management strategies. However, the genetic mechanism underlying the phenotypic differentiation between the inflection point and asymptotic stages of the growth curve is not well characterized. Here, w...
ORGANISM(S): Sus scrofa 
2015-05-25 | E-GEOD-69113 | biostudies-arrayexpress
ProteomicsUbiquitome profiling reveals the landscape of ubiquitination regulation in young panicle
Ubiquitome profiling reveals the landscape of ubiquitination regulation in young panicle
ORGANISM(S): Oryza Sativa 
2017-12-11 | PXD023306 |
ProteomicsDifferential Proteomic Analysis of Fetal and Geriatric Lumbar Nucleus Pulposus
Intervertebral disc degeneration (IVDD) is a main cause of degenerative disc disease, which results in substantial pain among patients. However, the mechanism of degeneration remains unclear. Thus far, basic research on human IVDD has focused on only a limited number of proteins and has not been con...
ORGANISM(S): Homo Sapiens 
PXD015000 |
ProteomicsProteomic analysis of PDCoV-infected HIEC-6 cells
Data-independent acquisition (DIA) is a new type of mass spectrometry data acquisition developed in recent years. The entire scanning range of mass spectrometry can be divided into several windows based on the mass-to-charge ratio (m/z), and then all the parent ions in each window are fragmented and...
ORGANISM(S): Homo Sapiens 
2024-02-20 | PXD049713 |
TranscriptomicsMapping of Hepatic Expression Quantitative Trait Loci (eQTLs) in a Han Chinese Population [SNP analysis]
Elucidating the genetic basis underlying the variation in hepatic gene expression is of importance to understand disease etiology and drug metabolism variances. To date, no genome-wide eQTL analysis has been conducted in the Han Chinese, the largest ethnic group in the world. We performed a genome-w...
ORGANISM(S): Homo sapiens 
2015-01-02 | E-GEOD-53790 | biostudies-arrayexpress
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